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Table 1 Baseline characteristics of the systemic sclerosis population (n = 40) and their correlations with galectin-3 and sST2 levels

From: Galectin-3 and sST2: associations to the echocardiographic markers of the myocardial mechanics in systemic sclerosis – a pilot study

Clinical variable Value Correlation with ln galectin-3 Correlations with ln galectin-3, corrected for age Correlations with ln sST2 Correlations with ln sST2, corrected for age
r p r p r p r p
Age (years) 57.3 ± 13.7 0.059 0.719    −0.010 0.951   
Body surface area (m2) 1.8 ± 0.2 0.206 0.202 0.206 0.208 0.063 0.700 0.063 0.704
Disease duration (years) 8.0 ± 6.2 0.406 0.009 0.406 0.010 0.038 0.817 0.042 0.799
Modified Rodnan skin score 12.6 ± 9.6 −0.291 0.069 −0.286 0.077 0.200 0.216 0.205 0.210
New York Heart Association functional class I n (%) 14 (35%) 0.179 0.269 0.171 0.297 −0.021 0.899 −0.018 0.912
II n (%) 16 (40%)
III n (%) 10 (25%)
6-min walking distance (m) 397.6 ± 78.3 −0.107 0.516 −.086 0.607 −0.001 0.996 0.001 0.996
Modified Borg dyspnoea index 1.8 ± 1.8 0.229 0.161 0.221 0.183 −0.234 0.151 −0.263 0.111
Forced expiratory volume in 1 s (%) 92.1 ± 15.5 −0.320 0.044 −0.334 0.032 −0.067 0.682 −0.066 0.689
Forced vital capacity (%) 94.9 ± 16.0 −0.246 0.126 −0.272 0.094 −0.157 0.333 −0.160 0.330
Diffusing capacity of carbon monoxide (%) 62.7 ± 16.2 −0.318 0.045 −0.324 0.044 0.106 0.515 0.123 0.456
Erythrocyte sedimentation rate (mm/h) 19.6 ± 13.5 −0.070 0.666 −0.079 0.633 0.099 0.545 0.101 0.541
C-reactive protein (mg/l) 4.2 ± 6.8 0.092 0.572 0.104 0.527 −0.118 0.468 −0.122 0.460
Creatinine (μmol/l) 63.8 ± 13.2 −0.013 0.936 −0.042 0.802 0.000 0.999 0.005 0.976
NT-proBNP (pg/ml; ln in correlations) 177.5 ± 148.6 0.094 0.566 0.081 0.623 −0.129 0.426 −0.131 0.425
Galectin-3 (ng/ml; ln in correlations) 12.9 ± 4.0      −0.217 0.178 −0.217 0.184
sST2 (ng/ml; ln in correlations) 28.5 ± 11.3 −0.217 0.178 −0.217 0.184     
  1. Statistically significant p-values (p < 0.05) are formatted in bold