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Table 1 Baseline characteristics of the systemic sclerosis population (n = 40) and their correlations with galectin-3 and sST2 levels

From: Galectin-3 and sST2: associations to the echocardiographic markers of the myocardial mechanics in systemic sclerosis – a pilot study

Clinical variable

Value

Correlation with ln galectin-3

Correlations with ln galectin-3, corrected for age

Correlations with ln sST2

Correlations with ln sST2, corrected for age

r

p

r

p

r

p

r

p

Age (years)

57.3 ± 13.7

0.059

0.719

  

−0.010

0.951

  

Body surface area (m2)

1.8 ± 0.2

0.206

0.202

0.206

0.208

0.063

0.700

0.063

0.704

Disease duration (years)

8.0 ± 6.2

0.406

0.009

0.406

0.010

0.038

0.817

0.042

0.799

Modified Rodnan skin score

12.6 ± 9.6

−0.291

0.069

−0.286

0.077

0.200

0.216

0.205

0.210

New York Heart Association functional class

I n (%)

14 (35%)

0.179

0.269

0.171

0.297

−0.021

0.899

−0.018

0.912

II n (%)

16 (40%)

III n (%)

10 (25%)

6-min walking distance (m)

397.6 ± 78.3

−0.107

0.516

−.086

0.607

−0.001

0.996

0.001

0.996

Modified Borg dyspnoea index

1.8 ± 1.8

0.229

0.161

0.221

0.183

−0.234

0.151

−0.263

0.111

Forced expiratory volume in 1 s (%)

92.1 ± 15.5

−0.320

0.044

−0.334

0.032

−0.067

0.682

−0.066

0.689

Forced vital capacity (%)

94.9 ± 16.0

−0.246

0.126

−0.272

0.094

−0.157

0.333

−0.160

0.330

Diffusing capacity of carbon monoxide (%)

62.7 ± 16.2

−0.318

0.045

−0.324

0.044

0.106

0.515

0.123

0.456

Erythrocyte sedimentation rate (mm/h)

19.6 ± 13.5

−0.070

0.666

−0.079

0.633

0.099

0.545

0.101

0.541

C-reactive protein (mg/l)

4.2 ± 6.8

0.092

0.572

0.104

0.527

−0.118

0.468

−0.122

0.460

Creatinine (μmol/l)

63.8 ± 13.2

−0.013

0.936

−0.042

0.802

0.000

0.999

0.005

0.976

NT-proBNP (pg/ml; ln in correlations)

177.5 ± 148.6

0.094

0.566

0.081

0.623

−0.129

0.426

−0.131

0.425

Galectin-3 (ng/ml; ln in correlations)

12.9 ± 4.0

    

−0.217

0.178

−0.217

0.184

sST2 (ng/ml; ln in correlations)

28.5 ± 11.3

−0.217

0.178

−0.217

0.184

    
  1. Statistically significant p-values (p < 0.05) are formatted in bold
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Cardiovascular Ultrasound

ISSN: 1476-7120

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