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Table 3 Correlations of galectin-3 (ln) and ST2 (ln) with the echocardiographic parameters of the LV and LA size and mechanics in SSc patients

From: Galectin-3 and sST2: associations to the echocardiographic markers of the myocardial mechanics in systemic sclerosis – a pilot study

Parameter Value Correlations with ln galectin-3 Correlations with ln galectin-3,
corrected for age
Correlations with ln ST2 Correlations with ln ST2,
corrected for age
r p r p r p r p
LV ejection fraction (%) 60.6 ± 4.6 −0.273 0.089 −0.267 0.100 0.082 0.614 0.082 0.618
LV GLS (%) −17.5 ± 2.3 0.454 0.005 0.460 0.005 0.003 0.988 − 0.007 0.969
LV mass index (g/m2) 93.5 ± 19.7 0.009 0.958 −0.039 0.814 −0.147 0.367 −0.184 0.262
Grade of mitral regurgitation Mild n (%) 37 (92.5%) 0.321 0.046 0.323 0.048 −0.078 0.637 −0.080 0.632
Moderate n (%) 3 (7.5%)
Severe n (%) 0 (0%)
Mitral E (cm/s) 73.9 ± 15.7 0.006 0.970 0.028 0.867 −0.022 0.892 −0.027 0.869
Mitral A (cm/s) 72.8 ± 16.9 0.320 0.044 0.334 0.038 0.132 0.417 0.156 0.342
Septal S (cm/s) 7.3 ± 1.2 −0.224 0.166 − 0.220 0.178 0.080 0.624 0.084 0.612
Septal e’ (cm/s) 7.4 ± 2.0 −0.306 0.055 −0.369 0.021 −0.088 0.591 −0.131 0.426
Septal a’ (cm/s) 8.7 ± 1.6 −0.012 0.939 −0.018 0.912 0.181 0.263 0.183 0.265
Septal E/e’ 10.5 ± 2.8 0.375 0.017 0.380 0.017 0.002 0.989 0.006 0.970
Lateral S (cm/s) 9.2 ± 1.8 −0.008 0.963 0.004 0.980 0.212 0.189 0.214 0.190
Lateral e’ (cm/s) 9.2 ± 2.8 −0.132 0.418 −0.119 0.471 0.019 0.906 0.016 0.922
Lateral a’ (cm/s) 10.6 ± 2.5 0.031 0.848 0.012 0.944 0.276 0.085 0.298 0.066
Lateral E/e’ 8.7 ± 3.0 0.109 0.502 0.106 0.522 −0.063 0.699 − 0.063 0.705
Averaged S (cm/s) 8.3 ± 1.3 −0.107 0.510 −0.093 0.573 0.182 0.261 0.189 0.248
Averaged e’ (cm/s) 8.3 ± 2.2 −0.224 0.165 −0.248 0.128 −0.027 0.867 −0.045 0.784
Averaged a’ (cm/s) 9.7 ± 1.7 0.017 0.918 −0.001 0.998 0.282 0.078 0.298 0.066
Averaged E/e’ 9.3 ± 2.3 0.252 0.117 0.246 0.132 −0.032 0.846 −0.030 0.856
Grade of LV diastolic function Normal n (%) 11 (27.5%) 0.325 0.040 0.394 0.013 −0.073 0.655 −0.091 0.582
Impaired relaxation (Grade I) n (%) 17 (42.5%)
Pseudonormal (Grade II) n (%) 12 (30%)
LA Vmax index (ml/m2) 22.8 ± 7.4 0.016 0.925 0.001 0.994 −0.294 0.081 −0.392 0.076
LA Vmin index (ml/m2) 10.3 ± 5.0 0.056 0.747 0.044 0.803 −0.305 0.071 −0.410 0.078
LA Vp index (ml/m2) 14.2 ± 6.1 0.095 0.580 0.088 0.617 −0.237 0.164 −0.360 0.111
LA reservoir strain (%) 43.0 ± 8.7 −0.148 0.383 −0.154 0.370 −0.045 0.790 −0.005 0.978
LA conduit strain (%) 23.5 ± 6.9 −0.117 0.491 −0.137 0.426 −0.066 0.700 0.005 0.979
LA contractile strain (%) 19.5 ± 4.8 −0.102 0.549 −0.106 0.538 0.012 0.945 −0.014 0.936
  1. Statistically significant p-values (p < 0.05) are formatted in bold