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Table 2 Comparison of parameters according to operation type at the second and third trimester

From: Fetal cardiac parameters for predicting postnatal operation type of fetuses with tetralogy of Fallot

Parameter

Study population (N = 100)

Single-stage surgery

(N = 90)

Multi-stage surgery

(N = 10)

P-value

At the second trimester

 PVA z-score

−3.3 (−6.4 ─ 2.2)

−3.1 (−5.8 ─ 2.2)

−4.1 (− 6.4 ─ -1.8)

0.014

 RPA z-score

−0.4 (− 3.1 ─ 1.8)

−0.3 (− 3.1 ─ 1.8)

−1.5 (− 2.0 ─ 0.3)

0.029

 AVA z-score

0.5 (−1.8 ─ 3.3)

0.5 (− 1.8 ─ 3.3)

0.3 (− 1.7 ─ 3.2)

0.625

 PV-PSV (m/s)

1.1 (0.7 ─ 1.6)

1.1 (0.7 ─ 1.6)

1.3 (1.2 ─ 1.6)

0.001

 PVA/AVA

0.77 (0.41 ─ 1.39)

0.78 (0.50 ─ 1.39)

0.67 (0.41 ─ 1.00)

0.152

 RPA/DAo

0.73 (0.45 ─ 1.12)

0.74 (0.45 ─ 1.12)

0.57 (0.52 ─ 0.81)

0.004

At the third trimester

 PVA z-score

−3.2 (−6.6 ─ -0.6)

− 3.0 (−5.4 ─ -0.6)

−5.0 (− 6.6 ─ -2.5)

<  0.001

 RPA z-score

− 0.5 (− 2.6 ─ 1.2)

− 0.4 (− 2.6 ─ 1.2)

− 0.9 (− 2.2 ─ 0)

0.022

 AVA z-score

1.0 (− 1.2 ─ 3.2)

1.0 (− 1.2 ─ 3.1)

0.9 (− 0.2 ─ 3.2)

0.732

 PV-PSV (m/s)

1.2 (0.8 ─ 2.8)

1.2 (0.8 ─ 2.8)

1.5 (1.2 ─ 1.8)

0.002

 PVA/AVA

0.76 (0.48 ─ 0.14)

0.77 (0.49 ─ 1.14)

0.60 (0.48 ─ 0.81)

<  0.001

 RPA/DAo

0.72 (0.47 ─ 0.98)

0.72 (0.47 ─ 0.98)

0.66 (0.51 ─ 0.79)

0.058

  1. Data are expressed as medians (ranges)
  2. PVA pulmonary valve annulus, RPA right pulmonary artery, AVA aortic valve annulus, PV-PSV pulmonary valve peak systolic velocity, DAo descending aorta