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Table 1 Demographics and High Spectrum Signal Intensity Coefficient (HS-SIC) values for clinical population, mean ± standard error of the mean

From: Cardiac microstructural alterations in immune-inflammatory myocardial disease: a retrospective case-control study

Population

N

Age

Male

Diabetes

HTN

HLD

Smoking

CAD

EF

HS-SIC (SEM)

P-Value (vs control)

Healthy Controls

20

34.7 ± 7.4

2 (10%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

65.7 ± 4.1

0.688 ± 0.074

Patient Cohorts

 Atypical Chest Pain or Palpitations

127

37.3 ± 12.8

76 (60%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

62.5 ± 4.5

0.552 ± 0.049

0.016

 Myocarditis

44

40.0 ± 17.1

12 (27%)

7 (15%)

20 (45%)

15 (34%)

11 (25%)

11 (25%)

48.5 ± 16.5

0.425 ± 0.058

0.001

 TTR Amyloidosis

25

76.3 ± 9.7

6 (24%)

6 (24%)

17 (68%)

19 (76%)

9 (36%)

6 (24%)

46.6 ± 16.9

0.698 ± 0.103

0.85

 STEMI

20

59.1 ± 20.4

6 (30%)

1 (5%)

15 (75%)

16 (80%)

9 (45%)

20 (100%)

40.3 ± 12.9

0.881 ± 0.129

0.30

 COVID

39

67.6 ± 16.4

28 (72%)

14 (36%)

25 (64%)

13 (33%)

8 (21%)

7 (18%)

57.2 ± 10.8

0.904 ± 0.116

0.58

 Severe Aortic Stenosis

21

82.3 ± 9.7

8 (38%)

5 (25%)

18 (90%)

16 (80%)

8 (40%)

14 (70%)

60.7 ± 11.8

1.116 ± 0.196

0.38

Transplanted Cohorts

 No prior or active rejection

5

49.6 ± 14.1

5 (100%)

3 (60%)

3 (60%)

3 (60%)

1 (20%)

1 (20%)

55.8 ± 1.9

1.191 ± 0.442

0.33

 Prior but no active rejection

15

54.9 ± 20.6

10 (67%)

8 (53%)

9 (60%)

3 (20%)

4 (27%)

2 (13%)

61.8 ± 3.8

0.594 ± 0.091

0.46

 Active rejection

22

48.5 ± 14.4

16 (73%)

10 (45%)

9 (41%)

9 (41%)

4 (18%)

5 (23%)

60.5 ± 6.8

0.478 ± 0.099

0.008

Total

338

49.6 ± 20.9

169 (50%)

54 (16%)

116 (34%)

94 (28%)

54 (16%)

66 (20%)

57.4 ± 12.3

0.656 ± 0.032

  1. HTN Hypertension, HLD Hyperlipidemia, CAD Coronary artery disease, EF Ejection Fraction