Table 4 Diagnostic performance of cut-off values to detect patients with decompensation and overt LVF

Decompensated LVD (PCWP ≥ 15 mmHg)

 NT-proBNP

 ≥ 2000 ng/L

75 (60–83)

73 (58–84)

2.7 (1.7–4.8)

0.37 (0.23–0.59)

 LVEF

 < 27%

69 (56–79)

69 (54–81)

2.2 (1.4–3.6)

0.45 (0.29–0.69)

 Standard echocardiography

91(80–97)

68 (49–82)

2.8 (1.7–4.9)

0.13 (0.05–0.33)

 RVD score

 ≥ 1

96 (88–99)

41 (26–58)

1.6 (1.2–2.2)

0.09 (0.02–0.37)

 RVD score

 ≥ 2

76 (64–86)

85 (70–94)

5.2 (2.3–11.8)

0.28 (0.17–0.46)

Overt LVF (PCWP ≥ 15 mmHg and SvO₂ < 60%)

 NT-proBNP

 ≥ 3100 ng/L

82 (66–91)

77 (65–85)

3.5 (2.2–5.6)

0.24 (0.11–0.50)

 LVEF

 < 25%

61 (44–75)

69 (57–78)

1.9 (1.2–3.0)

0.57 (0.37–0.90)

 Standard echocardiography

73 (54–86)

74 (60–85)

2.9 (1.7–4.9)

0.36 (0.19–0.70)

 RVD score

 ≥ 2

97 (84–99)

72 (59–82)

3.5 (2.3–5.3)

0.04 (0.006–0.30)

 RVD score

 ≥ 4

47 (31–64)

93 (83–97)

6.7 (2.4–18.4)

0.57 (0.41–0.80)