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Table 2 Echocardiography measurements at rest

From: Myocardial contrast echocardiography assessment of perfusion abnormalities in hypertrophic cardiomyopathy

 

Control Subjects

HCM Subjects

(n = 15)

(n = 15)

LVIDd (cm)

4.7 ± 0.6

4.3 ± 0.6

LVIDs (cm)

3.2 ± 0.8

2.7 ± 0.5

LV end-diastolic volume (mL)

102 ± 25

72 ± 18*

LV end-systolic volume (mL)

38 ± 10

30 ± 10

IVSd (cm)

0.9 ± 0.3

1.9 ± 0.4*

PWd (cm)

1.0 ± 0.3

1.2 ± 0.4

LVEF (%)

63 ± 7

72 ± 8*

Stroke volume (mL)

71 ± 10

80 ± 25

Stroke volume index (mL/m2)

34 ± 11

38 ± 11

Cardiac output (L/min)

4.9 ± 0.7

4.9 ± 1.2

Resting LVOT gradient (mm Hg) [IQR]

4 [3–6]

26 [8–52]*

LV stroke work index (g/m)

42 ± 10

98 ± 65*

LV myocardial work index (g/m/min)a

2870 ± 855

6014 ± 3720*

  1. IVSd Diastolic interventricular septum thickness, LVEDD Left ventricular end-diastolic volume, LVEF Left ventricular ejection fraction, LVESD Left ventricular end-systolic volume, LVIDd Diastolic left ventricular diameter, LVIDs Systolic left ventricular diameter, PWd Diastolic posterior wall thickness
  2. aLoad component in HCM subjects calculated by summing mean arterial pressure and peak LVOT gradient
  3. *p < 0.05 versus control subjects