Skip to main content

Table 3 Baseline echocardiographic characteristics of patients with SLE compared with healthy control subjects

From: Evaluation of left ventricular systolic function in patients with systemic lupus erythematosus using ultrasonic layer-specific strain technology and its association with cardiovascular events: a long-term follow-up study

Variable

SLE group (n = 162)

Healthy controls (n = 68)

P-value

IVSd (mm)

8.4 ± 1.3

7.6 ± 1.1

 < 0.001

LVEDd (mm)

44.5 ± 4.6

41.8 ± 3.8

 < 0.001

PW (mm)

7.4 ± 1.0

6.8 ± 1.0

 < 0.001

EDV (ml)

87.1 ± 18.3

79.5 ± 15.5

0.003

ESV (ml)

34.1 ± 8.8

29.9 ± 6.9

0.001

SV (ml)

53.0 ± 10.9

50.2 ± 9.0

0.026

LVEF (%)

60.6 ± 4.4

62.6 ± 2.4

0.007

RWT

0.36 ± 0.04

0.34 ± 0.04

0.056

LVM (g)

108.9 (86.3, 133.1)

88.4 (65.1, 101.8)

 < 0.001

LVMI (g/m2)

68.4 (54.2, 84.1)

54.4 (42.5, 64.2)

 < 0.001

LAVI (ml/m2)

26.0 ± 5.5

24.1 ± 4.7

0.086

E (cm/s)

79.5 (68.6, 92.5)

101.4 (87.6, 105.5)

 < 0.001

e′ (cm/s)

12.2 ± 1.8

13.1 ± 1.5

 < 0.001

E/e′

6.6 ± 1.1

7.2 ± 1.4

0.001

sPAP (mm Hg)

30.0 ± 8.7

24.5 ± 5.8

 < 0.001

LV diastolic dysfunction (%)

7 (4.3)

0 (0)

0.072

Endocardial LS (%)

-22.0 ± 3.4

-24.8 ± 2.9

 < 0.001

Mid-myocardial LS (%)

-19.6 ± 3.1

-22.4 ± 2.7

 < 0.001

Epicardial LS (%)

-18.6 ± 2.8

-20.5 ± 2.5

 < 0.001

LS gradient (%)

-3.4 ± 0.9

-4.5 ± 1.0

 < 0.001

Endocardial CS (%)

-29.7 ± 3.7

-33.1 ± 3.1

 < 0.001

Mid-myocardial CS (%)

-18.1 ± 3.2

-21.31 ± 2.7

 < 0.001

Epicardial CS (%)

-12.4 ± 3.0

-14.6 ± 2.6

 < 0.001

GCS gradient (%)

-17.3 ± 1.1

-18.5 ± 1.1

 < 0.001

  1. NOTE: IVSd interventricular septum diastolic, LVEDd left ventricular end-diastolic diameter PW posterior wall thickness, EDV end-diastolic volume, ESV end-systolic volume, SV stroke volume, LVEF left ventricular ejection fraction, RWT relative wall thickness, LVM left ventricular mass, LVMI left ventricular mass index, LAVI left atrial volume index, E early-diastolic velocity; e′, the average values of early-diastolic velocities at the septal and lateral mitral annulus; E/e′, E/e′ ratio; sPAP systolic pulmonary artery pressure, LS longitudinal strain, CS circumferential strain
  2. Values are expressed as mean ± standard deviation as median (interquartile range)
  3. Bold indicates statistically significant values