Table 4 Cox regression uni- and multivariate analyses for the occurrence of cardiovascular events in patients with SLE

Age

1.045 (1.021–1.073)

0.031

1.160 (0.339–3.375)

0.471

Sex, female

0.728 (0.264–2.011)

0.540

Systolic blood pressure

1.021 (1.005–1.038)

0.010

0.984 (0.959–1.089)

0.223

Diabetes mellitus

1.320 (0.781–2.170)

0.312

SLEDAI-2000 score

1.030 (1.011–1.050)

0.008

1.019 (0.994–1.044)

0.162

Positive anti-double-stranded DNA

1.356 (0.813–2.261)

0.244

Positive antiphospholipid antibodies

1.396(0.765–2.548)

0.277

Glucocorticoids

0.956 (0.565–1.618)

0.868

IVSd

0.983 (0.799–1.208)

0.868

LVEDd

0.997 (0.943–1.055)

0.926

EDV

1.006 (0.991–1.021)

0.462

LVEF

0.962 (0.910–1.018)

0.962

LVM

1.001 (0.991–1.021)

0.802

E/ e′

0.973 (0.784–1.207)

0.801

sPAP

1.064 (1.041–1.088)

 < 0.001

1.018 (0.848–1.431)

0.056

Endocardial LS

1.055 (1.031–1.156)

 < 0.001

1.014 (1.002–1.035)

0.025

LS gradient

1.076 (0.701–1.645)

0.738

Endocardial CS

2.508 (1.501–4.191)

 < 0.001

1.051 (1.027–1.077)

 < 0.001

CS gradient

1.114 (0.811–1.529)

0.505