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Table 2 Comparison of echocardiographic parameters between ASD patients and normal controls

From: Noninvasive right ventricular work in patients with atrial septal defects: a proof-of-concept study

Variables

ASD (n = 29)

Control (n = 29)

P-value

LVEF (%)

63.6 ± 3.4

64.7 ± 2.9

0.173

TAPSE (mm)

25.4 ± 3.6

20.2 ± 3.6

<0.001

RV FAC (%)

46.6 ± 3.7

47.1 ± 4.4

0.689

RV Sʹ (cm/s)

15.0 ± 3.0

13.1 ± 1.8

0.004

3D RV end-diastolic volume (mL)

153 (117–193)

91 (79–98)

<0.001

3D RV end-systolic volume (mL)

67 (44–80)

37 (34–40)

<0.001

3D RV stroke volume (mL)

89 ± 25

53 ± 7

<0.001

3D RV EF (%)

57.6 ± 3.3

58.6 ± 1.9

0.140

RV basal diameter (mm)

44.7 ± 7.8

34.4 ± 3.7

<0.001

TA diameter (mm)

36.8 ± 6.2

26.9 ± 3.7

<0.001

3D RA maximum volume (mL)

50 (43–64)

36 (34–39)

<0.001

SPAP (mmHg)

35.4 (29.1–48.4)

21.9 (18.6–25.6)

<0.001

DPAP (mmHg)

21.1 (18.0-27.3)

16.3 (13.6–18.6)

<0.001

MPAP (mmHg)

25.9 (22.2–34.2)

13.6 (11.2–15.7)

<0.001

RV FWLS (%)

-25.2 ± 3.8

-24.4 ± 3.5

0.401

RV GLS (%)

-22.3 ± 3.0

-20.7 ± 2.6

0.030

RVGWI (mmHg%)

571.7 ± 203.2

311.2 ± 98.7

<0.001

RVGCW (mmHg%)

690.8 ± 254.8

361.5 ± 101.3

<0.001

RVGWW (mmHg%)

56.0 (37.5–75.0)

22.0 (9.0-37.5)

<0.001

RVGWE (%)

91.0 (89.0–93.0)

92.0 (89.0–97.0)

0.214

  1. Data are presented as mean ± SD or median (interquartile range). 3D Three-dimensional, ASD Atrial septal defect, DPAP Diastolic pulmonary artery pressure, EF Ejection fraction, FAC Fractional area change, FWLS Free wall longitudinal strain, GLS Global longitudinal strain, LVEF Left ventricular ejection fraction, MPAP Mean pulmonary arterial pressure, RA Right atrial, RV Right ventricular, RVGCW RV global constructive work, RVGWE RV global work efficiency, RVGWI RV global work index, RVGWW RV global work waste, Sʹ, tissue Doppler-derived tricuspid lateral annular systolic velocity, SPAP Systolic pulmonary artery pressure, TA Tricuspid annular, TAPSE TA plane systolic excursion