Noninvasive right ventricular work in patients with atrial septal defects: a proof-of-concept study

Table 5 ROC analysis of echocardiographic parameters to identify atrial septal defect

Variables	AUC (SE)	P-value	AUC (95% CI)	Cutoff value	Sensitivity	Specificity
TAPSE (mm)	0.842 (0.050)	<0.001	0.744–0.940	20.2	96.6%	58.6%
RV-FAC (%)	0.499 (0.080)	0.994	0.342–0.656	43.9	86.2%	37.9%
RV Sʹ (cm/s)	0.713 (0.068)	0.005	0.580–0.846	13.5	69.0%	62.1%
3D RV EF (%)	0.365 (0.077)	0.078	0.215–0.516	61.6	20.7%	96.6%
RV FWLS (%)	0.553 (0.077)	0.489	0.403–0.703	-25.4	48.3%	69.0%
RV GLS (%)	0.656 (0.073)	0.042	0.514–0.798	-19.8	86.2%	48.3%
RVGWI (mmHg%)	0.895 (0.040)	<0.001	0.816–0.974	376.5	86.2%	82.8%
RVGCW (mmHg%)	0.922 (0.034)	<0.001	0.855–0.989	430.0	93.1%	82.8%
RVGWW (mmHg%)	0.870 (0.045)	<0.001	0.782–0.957	45.5	69.0%	86.2%
RVGWE (%)	0.405 (0.077)	0.216	0.255–0.556	87.5	86.2%	17.2%

3D Three-dimensional, AUC The area under receiver operating characteristic curve, CI Confidence interval, EF Ejection fraction, FAC Fractional area change, FWLS Free wall longitudinal strain, GLS Global longitudinal strain. ROC Receiver operating characteristic, RV Right ventricular, RVGCW RV global constructive work, RVGWE RV global work efficiency, RVGWI RV global work index, RVGWW RV global work waste, Sʹ Tissue Doppler-derived tricuspid lateral annular systolic velocity, SE Standard error, TAPSE Tricuspid annular plane systolic excursion

ISSN: 1476-7120