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Table 1 Left ventricular parameters during vena cava occlusion, first and last beat

From: Left ventricular twist is load-dependent as shown in a large animal model with controlled cardiac load

CONTROL

 

First beat

Last beat

 

Ves

(mL)

42.0 ± 7.9

21.3 ± 6.4

#

Ved

(mL)

100.3 ± 12.7

69.2 ± 11.0

#

Pes

(mm Hg)

118.6 ± 4.5

100.7 ± 6.6

#

Ped

(mm Hg)

12.0 ± 4.3

1.9 ± 3.7

#

dPdtMax

(mm Hg/s)

2797 ± 429

3035 ± 526

#

EF

(%)

61.9 ± 6.2

70.5 ± 7.0

#

SW

(mm Hg mL)

7097 ± 1385

4544 ± 891

#

Tau

(ms)

34.30 ± 2.77

34.10 ± 3.61

 

PHT

(ms)

20.85 ± 2.12

19.06 ± 2.56

 

dPdtMin

(mm Hg/s)

−2776 ± 186

−2347 ± 158

 

ADRENALINE

Ves

(mL)

32.0 ± 13.10

11.0 ± 7.4

#

Ved

(mL)

96.0 ± 32.4

62.9 ± 20.3

#

Pes

(mm Hg)

123.1 ± 18.0

98.0 ± 12.3

#

Ped

(mm Hg)

14.0 ± 6.9

3.0 ± 4.6

#

dPdtMax

(mm Hg/s)

5389 ± 1519

5416 ± 1538

 

EF

(%)

72.6 ± 7.2

85.0 ± 9.7

#

SW

(mm Hg mL)

8725 ± 2833

5822 ± 2415

#

Tau

(ms)

24.12 ± 2.87

31.11 ± 2.80

#

PHT

(ms)

14.92 ± 2.24

16.54 ± 1.66

 

dPdtMin

(mm Hg/s)

−3454 ± 775

−2314 ± 392

 

BETA-BLOCKADE

Ves

(mL)

52.2 ± 9.7

23.5 ± 10.9

#

Ved

(mL)

105.1 ± 20.0

62.0 ± 14.3

#

Pes

(mm Hg)

115.5 ± 12.7

91.7 ± 9.3

#

Ped

(mm Hg)

12.9 ± 5.6

−0.6 ± 4.3

#

dPdtMax

(mm Hg/s)

1925 ± 527

1909 ± 473

 

EF

(%)

55.4 ± 6.5

69.5 ± 16.7

#

SW

(mm Hg mL)

5907 ± 1675

3375 ± 826

#

Tau

(ms)

47.14 ± 20.61

36.84 ± 7.06

#

PHT

(ms)

26.40 ± 6.62

20.76 ± 5.06

#

dPdtMin

(mm Hg/s)

−2244 ± 414

−1992 ± 341

 
  1. Ves = end-systolic volume; Ved = end-diastolic volume; Pes = end-systolic pressure; Ped = end-diastolic pressure; dPdt max = maximal rate of pressure increase; EF = ejection fraction; SW = stroke work; Tau = isovolumic relaxation time constant; PHT = pressure half time during diastole: dPdt min = maximal rate of pressure decrease. Data are presented as mean ± 95% confidence intervals, n = 7. # = p < 0.05 using Wilcoxons Signed Rank test vs. first beat.