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Table 1 Baseline characteristics in overall patients and according to final diagnosis

From: Rapid evaluation by lung-cardiac-inferior vena cava (LCI) integrated ultrasound for differentiating heart failure from pulmonary disease as the cause of acute dyspnea in the emergency setting

 

All patients (n = 90)

AHFS group (n = 53)

Pulmonary group (n = 37)

P value

Mean age, yrs

78.1 ± 9.9

77.7 ± 10.3

78.6 ± 9.2

0.662

Female sex

45 (50.0)

29 (54.7)

16 (43.2)

0.284

Medical history

 Prior hospitalization for heart failure

42 (46.7)

27 (50.9)

15 (40.5)

0.330

 Hypertension

51 (56.7)

38 (71.7)

13 (35.1)

<0.001

 Dyslipidemia

20 (22.2)

16 (30.2)

4 (10.8)

0.029

 Diabetes

11 (12.2)

7 (13.2)

4 (10.8)

0.733

 Chronic obstructive pulmonary disease

24 (26.7)

13 (24.5)

11 (29.7)

0.583

 History of atrial fibrillation

22 (24.4)

12 (22.6)

10 (27.0)

0.634

Medications prior to admission

 Loop diuretic

47 (52.2)

31 (58.5)

16 (43.2)

0.154

 Spironolactone or Eplerenone

31 (34.4)

22 (41.5)

9 (24.3)

0.091

 ACE inhibitor or ARB

45 (50.0)

33 (62.3)

12 (32.4)

0.005

 Beta-blocker

27 (30.0)

17 (32.1)

10 (27.0)

0.607

 Calcium channel blocker

13 (14.4)

9 (16.9)

4 (10.8)

0.413

 Digoxin

8 (8.9)

6 (11.3)

2 (5.4)

0.332

Laboratory data

 Brain natriuretic peptide, pg/ml

461.1 ± 451.9

622.0 ± 505.3

230.7 ± 208.2

<0.001

 Blood urea nitrogen, mg/dl

25.6 ± 14.3

26.0 ± 15.2

24.8 ± 13.0

0.701

 Serum creatinine, mg/dl

1.07 ± 0.51

1.12 ± 0.58

0.99 ± 0.36

0.203

 C-reactive protein, mg/dl

3.64 ± 5.73

1.96 ± 3.17

6.05 ± 7.52

<0.001

Symptoms on admission

 Orthopnea

42 (46.7)

25 (47.2)

17 (45.9)

0.901

 Paroxysmal nocturnal dyspnea

40 (44.4)

28 (52.8)

12 (32.4)

0.055

 Peripheral edema

48 (53.3)

37 (69.8)

11 (29.7)

<0.001

Signs on admission

 Rales

56 (62.2)

37 (69.8)

19 (51.3)

0.075

 Wheezing

38 (42.2)

20 (37.7)

18 (48.6)

0.302

 Jugular venous distension

25 (27.8)

19 (35.8)

6 (16.2)

0.041

 S3

19 (21.1)

15 (28.3)

4 (10.5)

0.045

Ultrasound findings

 Pleural effusion

18 (20.0)

14 (26.4)

4 (10.5)

0.069

 Lung consolidation

10 (11.1)

1 (1.9)

9 (24.3)

<0.001

 Reduced EF (LVEF <40%)

22 (24.4)

16 (17.8)

6 (16.2)

0.129

 MR ≥ moderate

41 (45.6)

41 (77.3)

0 ( 0.0)

<0.001

 TR ≥ moderate

38 (42.2)

34 (64.5)

4 (10.5)

<0.001

 IVC collapsibility <50%

51 (56.7)

44 (83.0)

7 (18.9)

<0.001

  1. Values are shown as the no. (%), mean ± SD. AHFS = acute heart failure syndromes; ACE = angiotensin-converting enzyme; ARB = angiotensin receptor blocker. LV = left ventricular; EF = ejection fraction; MR = mitral reguragitation; TR = tricuspid regurgitation; IVC = inferior vena cava.