Transthoracic echocardiography reference values in juvenile and adult 129/Sv mice

Table 2 Echocardiographic measurements from M-mode images

Measurement	Juvenile	n	Adult	n	p
LVAWd (mm)	0.61 ± 0.09	15	0.74 ± 0.14	15	0.005
LVAWs (mm)	0.85 ± 0.13	15	1.08 ± 0.18	15	< 0.001
LVIDd (mm)	2.84 ± 0.20	15	3.56 ± 0.19	15	< 0.001
LVIDs (mm)	1.96 ± 0.21	15	2.44 ± 0.28	15	< 0.001
LVPWd (mm)	0.59 ± 0.15	15	0.64 ± 0.13	15	ns
LVPWs (mm)	0.81 ± 0.17	15	0.88 ± 0.19	15	ns
EF (%)	59.63 ± 9.05	15	59.91 ± 8.15	15	ns
FS (%)	30.76 ± 6.15	15	31.45 ± 5.63	15	ns
IVSd (mm)	0.41 ± 0.08	15	0.47 ± 0.15	15	ns
IVSs (mm)	0.50 ± 0.13	15	0.62 ± 0.25	15	ns
RVIDd (mm)	1.08 ± 0.15	7	1.42 ± 0.19	11	0.001
RVIDs (mm)	0.65 (0.31)	7	0.89 (0.21)	11	ns
RVAWd (mm)	0.50 ± 0.11	7	0.32 ± 0.08	11	0.001
RVAWs (mm)	0.66 ± 0.16	7	0.57 ± 0.13	11	ns

Values are mean ± SD or median (IQR), as appropriate. p = statistical significance. ns = not significant. n = 15 for all measurements, except for RV measurements (n = 7 for the juveniles and n = 11 for the adults).
LVAW = Left ventricle anterior wall. LVID = Left ventricle internal diameter. LVPW = Left ventricle posterior wall. EF = Ejection fraction. FS = Fractional shortening. IVS = Interventricular septum. RVID = Right ventricle internal diameter. RVAW = Right ventricle anterior wall. -d = In diastole. -s = In systole.

ISSN: 1476-7120