|
Univariate analysis
|
Multivariate analysis
|
|---|
|
Variables
|
HR
|
95% CI
|
p value
|
HR
|
95% CI
|
p value
|
|---|
|
RVOT-FS
|
0.110
|
0.014-0.886
|
0.038
|
0.028
|
0.002-0.397
|
0.008
|
|
NYHA functional class III-IV
|
2.828
|
1.380-5.793
|
0.004
|
2.233
|
1.048-4.761
|
0.037
|
|
IVSTd
|
0.112
|
0.030-0.415
|
0.001
| | | |
|
Diuretic use
|
6.872
|
1.654-28.548
|
0.008
| | | |
|
BNP
|
1.000
|
1.000-1.001
|
0.018
| | | |
|
Total bilirubin
|
1.675
|
1.217-2.306
|
0.002
| | | |
- Univariate and multivariate Cox regression analyses were constructed with forward step-wise variable selection. HR hazard ratio, CI confidence interval. Covariates included age (year), sex (male, 1; female, 2); NYHA functional class III-IV (0, I-II; 1, III-IV); sinus rhythm in electrocardiogram (no, 0; yes, 1); BNP (pg/mL), eGFR (mL/min/1.73 m2), hemoglobin (g/dL), total bilirubin (mg/dL), uric acid (mg/dL) and C-reactive protein (mg/dL), echocardiographic parameters such as LAD (cm), IVSTd (cm), LVDd (cm), LVEF (%), RVFAC (%), RVOT-FS, TR-PG (mmHg); use (no, 0; yes, 1) of beta-blocker, ACE-I/ARB, calcium channel blocker, diuretic and aldosterone antagonist.
