Table 1 Echocardiographic evaluation for each group

Gr 1 (N=14)

Gr 2 (N=14)

p (Gr 1 vs. Gr 2)

Gr 1 (N=14)

Gr 2 (N=14)

p (Gr 1 vs. Gr 2)

Gr 1 (N=8)

Gr 2 (N=8)

p (Gr 1 vs. Gr 2)

Adenine 0.5%

Controls

Adenine 0.5%

Controls

Adenine 0.5%

Controls

EF (%)

83 ± 2

84 ± 1

0.690

67 ± 3 **

75 ± 1 **

0.013

78 ± 1 *#

74 ± 3 *

0.328

CO (ml/min)

171 ± 11

163 ± 11

0.616

95 ± 6 **

185 ± 6 *

< 0.001

214 ± 18 #

207 ± 7

0.738

E/A

1.72 ± 0.18

1.61 ± 0.07

0.970

1.53 ± 0.06

1.52 ± 0.05

0.881

1.48 ± 0.09

1.51 ± 0.07

0.787

Dec time (ms)

44 ± 2

43 ± 1

0.707

45 ± 3

42 ± 2

0.522

47 ± 2

42 ± 2

0.103

AV Area (mm²)

5.1 ± 0.2

4.6 ± 0.3

0.217

5.1 ± 0.4

6.0 ± 0.4 *

0.095

9.5 ± 1.2 *#

8.2 ± 0.7 *#

0.505

Aortic Peak PG (mmHg)

1.77 ± 0.13

1.64 ± 0.10

0.329

0.97 ± 0.08 *

1.48 ± 0.17

0.020

1.46 ± 0.16 #

1.67 ± 0.12

0.317

Aortic Mean PG (mmHg)

1.30 ± 0.10

1.17 ± 0.07

0.376

0.68 ± 0.05 *

1.02 ± 0.11

0.008

1.17 ± 0.08 #

1.18 ± 0.09

0.925