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Table 2 The prognostic value of contractility in the stress echo lab

From: Myocardial contractility in the stress echo lab: from pathophysiological toy to clinical tool

Author, year

Stress

Pts (n)

Inclusion criteria

LVEF

Median follow-up (months)

Best prognostic PVR cut-off

Considered events

Events n (%)

PPV

NPV

Grosu A et al., 2005 [7]

DOB

95

Medically treated pts with LV dysfunction

40±15%

18

<0.2 mmHg/ml/m2

Death, HF

18 (19%)

77%

89%

Otasevic P et al., 2006 [20]

DOB

59

Idiopathic dilated cardiomyopathy

19±8%

60

<0.33 mmHg/ml/m2

Death

27 (46%)

62%

84%

Bombardini T et al., 2008 [15]

EX

99

Medically treated pts with negative stress

47±14%

21

<2.2 mmHg/ml/m2

Death, HF, ↑NYHA

29 (29%)

62%

98%

Agricola E et al., 2008 [23]

EX

37

Functional MR in LV dysfunction

29±7%

20

<0.4 mmHg/ml/m2

Death

8 (22%)

35%

93%

Ciampi Q et al., 2010 [24]

DOB

72

Identification of CRT responders

26±6%

12

<0.7 mmHg/ml/m2

Death, HF

22 (31%)

40%

91%

Bombardini T et al., 2011 [17]

DIP

16

Recipients of older donor hearts

56±6%

14

<0 mmHg/ml/m2

Death

2 (13%)

50%

94%

Bombardini T et al., 2013 [25]

EX

172

Followed-up Pts with negative stress

53±14%

32

<1.34 mmHg/ml/m2

Death, HF

29

55%

96%

DIP

482

 

50±17%

21

<0.46 mmHg/ml/m2

Death, HF

68

24%

97%

DOB

237

 

39±15%

6

<0.56 mmHg/ml/m2

Death, HF

37

40%

94%

Cortigiani L et al., 2009 [19]

DOB

233

Diabetics with negative stress

52±10%

18

<12 mmHg/ml/m2

Death, PCI/CABG

62 (27%)

36%

83%

  1. CABG = Coronary artery by-pass grafting; CAD = Coronary artery disease; CRT = Cardiac resynchronization therapy; DIP = Dipyridamole; DOB = Dobutamine; EX = Exercise; HF = Heart failure; LV = Left ventricle; LVEF = Left ventricular ejection fraction; MR = Mitral regurgitation; NPV = Negative predictive value; PCI = Percutaneous coronary intervention; PPV = Positive predictive value; PVR = Pressure-volume relation.