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Table 2 The prognostic value of contractility in the stress echo lab

From: Myocardial contractility in the stress echo lab: from pathophysiological toy to clinical tool

Author, year Stress Pts (n) Inclusion criteria LVEF Median follow-up (months) Best prognostic PVR cut-off Considered events Events n (%) PPV NPV
Grosu A et al., 2005 [7] DOB 95 Medically treated pts with LV dysfunction 40±15% 18 <0.2 mmHg/ml/m2 Death, HF 18 (19%) 77% 89%
Otasevic P et al., 2006 [20] DOB 59 Idiopathic dilated cardiomyopathy 19±8% 60 <0.33 mmHg/ml/m2 Death 27 (46%) 62% 84%
Bombardini T et al., 2008 [15] EX 99 Medically treated pts with negative stress 47±14% 21 <2.2 mmHg/ml/m2 Death, HF, ↑NYHA 29 (29%) 62% 98%
Agricola E et al., 2008 [23] EX 37 Functional MR in LV dysfunction 29±7% 20 <0.4 mmHg/ml/m2 Death 8 (22%) 35% 93%
Ciampi Q et al., 2010 [24] DOB 72 Identification of CRT responders 26±6% 12 <0.7 mmHg/ml/m2 Death, HF 22 (31%) 40% 91%
Bombardini T et al., 2011 [17] DIP 16 Recipients of older donor hearts 56±6% 14 <0 mmHg/ml/m2 Death 2 (13%) 50% 94%
Bombardini T et al., 2013 [25] EX 172 Followed-up Pts with negative stress 53±14% 32 <1.34 mmHg/ml/m2 Death, HF 29 55% 96%
DIP 482   50±17% 21 <0.46 mmHg/ml/m2 Death, HF 68 24% 97%
DOB 237   39±15% 6 <0.56 mmHg/ml/m2 Death, HF 37 40% 94%
Cortigiani L et al., 2009 [19] DOB 233 Diabetics with negative stress 52±10% 18 <12 mmHg/ml/m2 Death, PCI/CABG 62 (27%) 36% 83%
  1. CABG = Coronary artery by-pass grafting; CAD = Coronary artery disease; CRT = Cardiac resynchronization therapy; DIP = Dipyridamole; DOB = Dobutamine; EX = Exercise; HF = Heart failure; LV = Left ventricle; LVEF = Left ventricular ejection fraction; MR = Mitral regurgitation; NPV = Negative predictive value; PCI = Percutaneous coronary intervention; PPV = Positive predictive value; PVR = Pressure-volume relation.
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