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Table 2 Sub-analysis of baseline characteristics according to the presence of left atrial abnormality

From: Which method of left atrium size quantification is the most accurate to recognize thromboembolic risk in patients with non-valvular atrial fibrillation?

Parameter Without LA ABN With LA ABN p
Demographics
Age (years) 68 ± 11 70 ± 8 0.02
Body Mass Index (Kg/m2) 26.8 ± 9 26 ± 8.1 0.4
Female gender 33% (116) 37.2% (55) 0.4
Clinical data
Hypertension 80.8% (284) 84.6% (125) 0.4
Diabetes 21.9% (77) 28% (41) 0.1
Previous Stroke/TIA 13.2% (46) 18.9% (28) 0.1
Congestive heart failure 50.4% (177) 65.7% (97) 0.002
Vascular diseasea 47.4% (167) 62.8% (93) 0.003
CHADS2 score 1.8 ± 1.2 2.1 ± 1.1 0.001
CHA2DS2-VASc score 3 ± 1.7 3.6 ± 1.6 <0.001
Pacemaker or ICD 18.8% (66) 21.7% (32) 0.7
Estimated current AF episode duration
≤ 48 hours 8.5% (30) 3.6% (5) 0.06
< 1 week 24% (84) 9.5% (14) <0.001
< 1 month 40% (141) 26.3% (39) 0.001
> 6 months 31% (109) 47.3% (70) 0.001
> 1 year 22.2% (78) 37.8% (51) 0.001
Echocardiographic characterization
LA AP diameter, (cm) 4.6 ± 0.7 4.8 ± 0.8 0.004
LA area (cm2) 26.4 ± 6.8 30.3 ± 7.1 <0.001
LA ellipsoid volume (cm3) 70.5 ± 28.2 82.1 ± 29.4 0.001
LA 1P area-length volume (cm3) 106.6 ± 45.9 130 ± 47.7 <0.001
LA 2P area-length volume (cm3) 97.6 ± 37.6 117 ± 35.9 <0.001
Indexed LA AP diameter, (cm/m2) 2.4 ± 0.5 2.7 ± 0.4 <0.001
Indexed LA area (cm2/m2) 14.2 ± 4.1 16.9 ± 4.1 <0.001
Indexed LA ellipsoid volume (cm3/m2) 37.6 ± 16.3 45.3 ± 16.3 <0.001
Indexed LA 1P area-length volume (cm3/m2) 56.9 ± 24.7 72.3 ± 26.9 <0.001
Indexed LA 2P area-length volume (cm3/m2) 51.9 ± 20.6 64.8 ± 20.9 <0.001
LV ejection fraction ≥55% 79.8% (281) 58.8% (87) <0.001
Medication previous to TEE
Oral Antiocagulation 36.6% (129) 50% (74) 0.01
Antiplatelet agents 48.8% (172) 40.5% (60) 0.1
1-3 doses of enoxaparine 36.1% (127) 28.3% (42) 0.1
Laboratorial evaluation
Haemoglobin (g/dL) 13.3 ± 1.9 13.1 ± 1.6 0.3
Platelets (103/μL) 220.6 ± 91.4 217.5 ± 69.4 0.7
INR 1.5 ± 0.8 1.5 ± 0.7 0.8
INR ≥ 2.0 20.7% (73) 20.9% (31) 0.96
GFR (mL/min/1.73 m2) 61.9 ± 33.1 63.8 ± 32.8 0.6
  1. Legend: GFR – glomerular filtration rate; ICD - implantable cardioverter defibrillator; INR – international normalized ratio; LV – left ventricle; TIA – transient ischaemic attack.
  2. aVascular disease is defined as having at least one of the following: myocardial infarctions, peripheral artery disease, and complex aortic plaque.