Table 2 Sub-analysis of baseline characteristics according to the presence of left atrial abnormality
Parameter | Without LA ABN | With LA ABN | p |
|---|---|---|---|
Demographics | |||
Age (years) | 68 ± 11 | 70 ± 8 | 0.02 |
Body Mass Index (Kg/m2) | 26.8 ± 9 | 26 ± 8.1 | 0.4 |
Female gender | 33% (116) | 37.2% (55) | 0.4 |
Clinical data | |||
Hypertension | 80.8% (284) | 84.6% (125) | 0.4 |
Diabetes | 21.9% (77) | 28% (41) | 0.1 |
Previous Stroke/TIA | 13.2% (46) | 18.9% (28) | 0.1 |
Congestive heart failure | 50.4% (177) | 65.7% (97) | 0.002 |
Vascular diseasea | 47.4% (167) | 62.8% (93) | 0.003 |
CHADS2 score | 1.8 ± 1.2 | 2.1 ± 1.1 | 0.001 |
CHA2DS2-VASc score | 3 ± 1.7 | 3.6 ± 1.6 | <0.001 |
Pacemaker or ICD | 18.8% (66) | 21.7% (32) | 0.7 |
Estimated current AF episode duration | |||
≤ 48 hours | 8.5% (30) | 3.6% (5) | 0.06 |
< 1 week | 24% (84) | 9.5% (14) | <0.001 |
< 1 month | 40% (141) | 26.3% (39) | 0.001 |
> 6 months | 31% (109) | 47.3% (70) | 0.001 |
> 1 year | 22.2% (78) | 37.8% (51) | 0.001 |
Echocardiographic characterization | |||
LA AP diameter, (cm) | 4.6 ± 0.7 | 4.8 ± 0.8 | 0.004 |
LA area (cm2) | 26.4 ± 6.8 | 30.3 ± 7.1 | <0.001 |
LA ellipsoid volume (cm3) | 70.5 ± 28.2 | 82.1 ± 29.4 | 0.001 |
LA 1P area-length volume (cm3) | 106.6 ± 45.9 | 130 ± 47.7 | <0.001 |
LA 2P area-length volume (cm3) | 97.6 ± 37.6 | 117 ± 35.9 | <0.001 |
Indexed LA AP diameter, (cm/m2) | 2.4 ± 0.5 | 2.7 ± 0.4 | <0.001 |
Indexed LA area (cm2/m2) | 14.2 ± 4.1 | 16.9 ± 4.1 | <0.001 |
Indexed LA ellipsoid volume (cm3/m2) | 37.6 ± 16.3 | 45.3 ± 16.3 | <0.001 |
Indexed LA 1P area-length volume (cm3/m2) | 56.9 ± 24.7 | 72.3 ± 26.9 | <0.001 |
Indexed LA 2P area-length volume (cm3/m2) | 51.9 ± 20.6 | 64.8 ± 20.9 | <0.001 |
LV ejection fraction ≥55% | 79.8% (281) | 58.8% (87) | <0.001 |
Medication previous to TEE | |||
Oral Antiocagulation | 36.6% (129) | 50% (74) | 0.01 |
Antiplatelet agents | 48.8% (172) | 40.5% (60) | 0.1 |
1-3 doses of enoxaparine | 36.1% (127) | 28.3% (42) | 0.1 |
Laboratorial evaluation | |||
Haemoglobin (g/dL) | 13.3 ± 1.9 | 13.1 ± 1.6 | 0.3 |
Platelets (103/μL) | 220.6 ± 91.4 | 217.5 ± 69.4 | 0.7 |
INR | 1.5 ± 0.8 | 1.5 ± 0.7 | 0.8 |
INR ≥ 2.0 | 20.7% (73) | 20.9% (31) | 0.96 |
GFR (mL/min/1.73 m2) | 61.9 ± 33.1 | 63.8 ± 32.8 | 0.6 |