Table 3 Selected parameters in patients with the high (subgroup H) and low (subgroup G) ET-1 levels in the pulmonary artery
From: Elevated level of plasma endothelin-1 in patients with atrial septal defect
Subgroup G – ET1 from 0,91 to 2,81 fmol/ml | Subgroup H – ET1 from 7,13 to 24,68 fmol/ml | P | |
|---|---|---|---|
Age | 35,1 ± 11,43 | 56,36 ± 5,7 | <0,001 |
Defect size | 23,1 ± 7,28 | 18,9 ± 4,28 | NS |
RV area (cm 2 ) | 23,1 ± 1,01 | 25 ± 1,51 | < 0,01 |
RA area (cm 2 ) | 16,2 ± 1,2 | 19,5 ± 0,9 | <0,001 |
PAPs (mmHg) | 20,1 ± 5,2 | 40,01 ± 19,5 | <0,01 |
Qp (l/min) | 8,4 ± 2,41 | 8,7 ± 2,5 | NS |
COP (dyn/s/cm −5 ) | 140,1 ± 24,8 | 189 ± 130,1 | NS |
Qp/Qs | 2,20 ± 1,31 | 2,34 ± 1,4 | NS |
T (s) | 734 ± 71,45 | 700,7 ± 90,1 | NS |
VO 2peak (ml/kg/min) | 24,13 ± 3,32 | 21,1 ± 3,92 | <0,05 |
FVC% | 107,6 ± 14,0 | 89,5 ± 4,7 | <0,05 |
FEV 1 % | 93,5 ± 10,2 | 87,3 ± 17 | NS |
T AT (s) | 455,6 ± 44,9 | 390 ± 23,1 | <0,01 |
VO 2AT % | 41,4 ± 2,8 | 35,41 ± 4,5 | <0,05 |
VE/VCO 2 | 30,4 ± 3,1 | 39 ± 4,4 | <0,05 |
NYHA | 1,9 ± 1,08 | 2,39 ± 1,03 | NS |