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Table 2 Characteristics of patients based on severity of aortic valve disease.

From: Validation of the severity index by cardiac catheterization and Doppler echocardiography in patients with aortic sclerosis and stenosis

Characteristic

Aortic Sclerosis n = 28

Mild-Mod AS n = 12

Severe AS n = 8

p value

Age (years, mean ± SD*)

56 ± 8

56 ± 13

59 ± 10

0.37

Gender Male/Female

20/8

8/4

4/4

0.54

Hypertension, n (%)

20 (71%)

8 (67%)

4 (50%)

0.54

Diabetes Mellitus, n (%)

10 (36%)

5 (42%)

2 (25%)

0.74

Hyperlipidemia, n (%)

13 (46%)

4 (33%)

3 (38%)

0.72

Smoking, n (%)

12 (43%)

3 (25%)

4 (50%)

0.45

Family History of CAD, n (%)

11 (39%)

4 (33%)

1 (13%)

0.32

Maximum Aortic Valve Gradient by Catheterization (mean ± SD*) (mm Hg)

7.0 ± 2.8

30 ± 16

83 ± 24

<0.0001

Transaortic Jet Velocity by Echocardiography, (mean ± SD*) (m/s)

1.29 ± 0.27

2.65 ± 0.70

4.54 ± 0.60

<0.0001

Severity Index (0 to 12) (mean ± SD*)

3.38 ± 1.06

6.45 ± 2.12

8.38 ± 1.41

<0.0001

AV Ca (1–6) (mean ± SD*)

2.2 ± 0.78

4.1 ± 1.6

5.5 ± 0.76

<0.0001

AV Mobility (1–4) (mean ± SD*)

1.2 ± 0.43

2.4 ± 0.67

3.3 ± 0.49

<0.0001

  1. CAD = coronary artery disease; AV Ca = aortic valve calcium; AV Mobility = aortic valve mobility; *SD = Standard Deviation