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Table 2 Characteristics of patients based on severity of aortic valve disease.

From: Validation of the severity index by cardiac catheterization and Doppler echocardiography in patients with aortic sclerosis and stenosis

Characteristic Aortic Sclerosis n = 28 Mild-Mod AS n = 12 Severe AS n = 8 p value
Age (years, mean ± SD*) 56 ± 8 56 ± 13 59 ± 10 0.37
Gender Male/Female 20/8 8/4 4/4 0.54
Hypertension, n (%) 20 (71%) 8 (67%) 4 (50%) 0.54
Diabetes Mellitus, n (%) 10 (36%) 5 (42%) 2 (25%) 0.74
Hyperlipidemia, n (%) 13 (46%) 4 (33%) 3 (38%) 0.72
Smoking, n (%) 12 (43%) 3 (25%) 4 (50%) 0.45
Family History of CAD, n (%) 11 (39%) 4 (33%) 1 (13%) 0.32
Maximum Aortic Valve Gradient by Catheterization (mean ± SD*) (mm Hg) 7.0 ± 2.8 30 ± 16 83 ± 24 <0.0001
Transaortic Jet Velocity by Echocardiography, (mean ± SD*) (m/s) 1.29 ± 0.27 2.65 ± 0.70 4.54 ± 0.60 <0.0001
Severity Index (0 to 12) (mean ± SD*) 3.38 ± 1.06 6.45 ± 2.12 8.38 ± 1.41 <0.0001
AV Ca (1–6) (mean ± SD*) 2.2 ± 0.78 4.1 ± 1.6 5.5 ± 0.76 <0.0001
AV Mobility (1–4) (mean ± SD*) 1.2 ± 0.43 2.4 ± 0.67 3.3 ± 0.49 <0.0001
  1. CAD = coronary artery disease; AV Ca = aortic valve calcium; AV Mobility = aortic valve mobility; *SD = Standard Deviation