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Table 3 Among women, the risk associated with RCCA B-mode ultrasound vascular measures and the model discrimination in the developmental and test data sets of the ARICLAD, 1987–99

From: Common carotid artery wall thickness and external diameter as predictors of prevalent and incident cardiac events in a large population study

  

Incident Cardiac Events

  

Vascular Measure Risk

Model Discrimination

  

Overall

Developmental

Test

Model

RCCA Measure

N = 6060

N = 3841

N = 2219

  

HR (95% CI)

AUC

AUC

1

IMT

1.49 (1.38–1.61)

0.621

0.608

2

IMT

1.40 (1.28–1.53)

0.682

0.675

3

IMT

1.19 (1.08–1.31)

0.830

0.805

1

diameter

2.01 (1.76–2.29)

0.696

0.679

2

diameter

1.83 (1.59–2.11)

0.724

0.712

3

diameter

1.26 (1.08–1.48)

0.831

0.812

1

Wall area

1.65 (1.52–1.78)

0.680

0.661

2

Wall area

1.56 (1.42–1.71)

0.702

0.699

3

Wall area

1.23 (1.10–1.38)

0.831

0.808

Model

Two Measures

HR (95% CI)

Developmental

Test

   

AUC

AUC

1

IMT +

diameter

1.26 (1.15–1.39)

1.75 (1.51–2.02)

0.705

0.674

2

IMT +

diameter

1.23 (1.10–1.37)

1.65 (1.42–1.93)

0.724

0.705

3

IMT +

diameter

1.14 (1.03–1.27)

1.18 (1.00–1.40)

0.831

0.805

  1. HR = hazards ratio for 1 standard deviation increment of the vascular measure in Cox proportional hazards models. CI: confidence interval
  2. Model 1: vascular measure(s) only; Model 2 covariates: age, race, and height;
  3. Model 3 covariates: age, race, systolic blood pressure, diabetes mellitus, HDL and LDL cholesterol, blood glucose, fibrinogen, current drinking, and current smoking.
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Cardiovascular Ultrasound

ISSN: 1476-7120

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