Table 1 Characteristics and echocardiographic data of the study animals

Body mass – g

   Mean

275

282

267

288

269

275

274

   SD

23

26

24

25

24

20

23

   Range

227–312

258–318

227–287

247–312

235–306

237–291

235–312

Heart rate – bpm

   Mean

263/261

265/274*

260/253

277/260

260/253

260/265

259/268

   SD

17/27

11/11

21/29

12/22

20/38

18/23

14/27

   Range

231–289/185–311

223–249/215–287

244–288/221–296

256–288/234–298

235–289/185 – 289

245–289/234 – 300

231–278/221–311

Enddiastolic diameter-mm

   Mean

7/7.2*

6.9/7.2*

6.7/7.1*

7.6/7.8

6.6/6.8

7.1/7.3

6.8/7.1

   SD

0.7/0.6

0.64/0.62

0.67/0.43

0.29/0.53

0.17/0.84

0.25/0.30

0.7/0.4

   Range

5.0–8.1/5.5–8.7

6.3–7.8/6.5–7.9

6.0–7.8/6.4 – 7.6

7.3–8.1/7.1 – 8.7

5.0–7.4/5.5 – 7.3

6.8–7.6/6.9–7.8

5.4–7.6/6.5–7.9

Endsystolic diameter- mm

   Mean

2.8/3.1*

2.7/3.0*

2.6/3.0*

2.7/3.3

2.5/2.7

2.6/2.8

2.5/2.7

   SD

0.6/0.7

0.6/0.67

0.56/0.65

0.54/0.62

0.4/0.45

0.37/0.34

0.34/0.27

   Range

2.1–4.1/2.1–4.0

2.2 – 4.0/2.3–4.1

2.3 – 4.1/2.4 – 4.2

2.5–4.1/2.6–4.0

2.2–4.0/2.3–4.1

2.3 – 4.1/2.2–4.1

2.3–4.0/2.3–4.1

Enddiastolic septal wall-mm

   Mean

1.3/1.3

1.3/1.3

1.3/1.2

1.2/1.2

1.6/1.5

1.2/1,2

1.4/1.4

   SD

0.20/0.22

0.14/0.09

0.3/0.11

0.08/0.10

0.23/0.17

0.08/0.05

0.33/0.33

   Range

1–2.0/1.1–2.0

1.2–1.5/1.2–1.4

1.1–1.8/1.1–1.4

1.1–1.3/1.1–1.4

1.3 – 2.0/1.2 – 1.7

1.1–1.3/1.1 – 1.2

1.0 – 1.9/1.1–1.4

Enddiastolic inferior wall-mm

   Mean

1.4/1.4

1.22/1.3

1.48/1.28

1.25/1.30

1.6/1.6

1.2/1.2

1.4/1.5

   SD

0.3/0.3

0.09/0.14

0.2/0.1

0.10/0.12

0.41/0.51

0.13/0.082

0.27/0.38

   Range

1.1–2.3/1.1–2.6

1.1–1.3/1.1–1.4

1.2 – 2.2/1.1.-1.4

1.1–1.4/1.1–1.4

1.2 – 2.3/1.2 – 2.6

1.1–1.4/1.1 – 1.3

1.1–1.9/1.2–2.3

Fractional shortening-%

   Mean

36.6/37.1

35.0/36.5

36.2/35.0

33.0/33.8

40. 0/43.2

34/35

39/38

   SD

4.9/5.2

1.5/1.5

3.5/2.7

1.8/2.2

5.2/6.1

2.5/2.3

6.3/5.5

   Range

31–52/31–53

34–36/35–38

34–42/32–39

32–34/31–37

34–47/37–53

31–37/32 – 38

32–52/31–45

Left ventricular ejection fraction-%

   Mean

73/74

71/72

71/70

74/74

75/78

71/72

74/74

   SD

5/4

2/4

5/3.5

2.5/2.1

6.7 – 6.9

1.7/2.5

7.3/4.9

   Range

62–87/66–88

68–73/66 – 75

67 – 79/66–75

71–78/71–76

67 – 83/70 – 88

68 – 73/69–74

62–87/67–81

Right ventricular enddiastolic diameter-mm

   Mean

3.4/3.5

3.5/3.6

3.4/3.6

3.4/3.7

3.34/3.45

3.3/3.5

3.2/3.4

   SD

0.16/0.14

0.14/0.13

0.22/0.21

0.21/0.23

0.16/0.21

0.21/0.22

0.19/0.22

   Range

3.3 – 4.0/3.5 – 4.1

3.4–4.1/3.4 – 4.3

3.3–4.0/3.2 – 4.3

3.4–4.1/3.3 – 4.3

3.4–4.1/3.2–4.3

3.2–3.9/3.4 – 4.1

3.4 – 3.9/3.4 – 4.1

Tricuspid annular plane Systolic excursion (TAPSE)-mm

   Mean

1.9/1.9

1.85/1.82

1.94/1.86

1.88/1.95

1.88/1.95

1.9/1.9

1.91/1.92

   SD

0.12/0.11

0.17/0.10

0.16/0.11

0.13/0.08

0.13/0.09

0.11/0.09

0.09/0.14

   Range

1.7 – 2.2/1.7–2.1

1.7 – 2.1/1.7 – 1.9

1.8–2.2/1.7–2.0

1.7–2.1/1.8–2.0

1.7–2.1/1.8–2.0

1.7–2.0/1.8–2.0

1.8–2.0/1.7–2.1