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Table 1 Characteristics and echocardiographic data of the study animals

From: Noninvasive monitoring of myocardial function after surgical and cytostatic therapy in a peritoneal metastasis rat model: assessment with tissue Doppler and non-Doppler 2D strain echocardiography

  Group 2–6 before/after therapy Group 1 Group 2 Group 3 Group 4 Group 5 Group 6
Body mass – g        
   Mean 275 282 267 288 269 275 274
   SD 23 26 24 25 24 20 23
   Range 227–312 258–318 227–287 247–312 235–306 237–291 235–312
Heart rate – bpm        
   Mean 263/261 265/274* 260/253 277/260 260/253 260/265 259/268
   SD 17/27 11/11 21/29 12/22 20/38 18/23 14/27
   Range 231–289/185–311 223–249/215–287 244–288/221–296 256–288/234–298 235–289/185 – 289 245–289/234 – 300 231–278/221–311
Enddiastolic diameter-mm        
   Mean 7/7.2* 6.9/7.2* 6.7/7.1* 7.6/7.8 6.6/6.8 7.1/7.3 6.8/7.1
   SD 0.7/0.6 0.64/0.62 0.67/0.43 0.29/0.53 0.17/0.84 0.25/0.30 0.7/0.4
   Range 5.0–8.1/5.5–8.7 6.3–7.8/6.5–7.9 6.0–7.8/6.4 – 7.6 7.3–8.1/7.1 – 8.7 5.0–7.4/5.5 – 7.3 6.8–7.6/6.9–7.8 5.4–7.6/6.5–7.9
Endsystolic diameter- mm        
   Mean 2.8/3.1* 2.7/3.0* 2.6/3.0* 2.7/3.3 2.5/2.7 2.6/2.8 2.5/2.7
   SD 0.6/0.7 0.6/0.67 0.56/0.65 0.54/0.62 0.4/0.45 0.37/0.34 0.34/0.27
   Range 2.1–4.1/2.1–4.0 2.2 – 4.0/2.3–4.1 2.3 – 4.1/2.4 – 4.2 2.5–4.1/2.6–4.0 2.2–4.0/2.3–4.1 2.3 – 4.1/2.2–4.1 2.3–4.0/2.3–4.1
Enddiastolic septal wall-mm        
   Mean 1.3/1.3 1.3/1.3 1.3/1.2 1.2/1.2 1.6/1.5 1.2/1,2 1.4/1.4
   SD 0.20/0.22 0.14/0.09 0.3/0.11 0.08/0.10 0.23/0.17 0.08/0.05 0.33/0.33
   Range 1–2.0/1.1–2.0 1.2–1.5/1.2–1.4 1.1–1.8/1.1–1.4 1.1–1.3/1.1–1.4 1.3 – 2.0/1.2 – 1.7 1.1–1.3/1.1 – 1.2 1.0 – 1.9/1.1–1.4
Enddiastolic inferior wall-mm        
   Mean 1.4/1.4 1.22/1.3 1.48/1.28 1.25/1.30 1.6/1.6 1.2/1.2 1.4/1.5
   SD 0.3/0.3 0.09/0.14 0.2/0.1 0.10/0.12 0.41/0.51 0.13/0.082 0.27/0.38
   Range 1.1–2.3/1.1–2.6 1.1–1.3/1.1–1.4 1.2 – 2.2/1.1.-1.4 1.1–1.4/1.1–1.4 1.2 – 2.3/1.2 – 2.6 1.1–1.4/1.1 – 1.3 1.1–1.9/1.2–2.3
Fractional shortening-%        
   Mean 36.6/37.1 35.0/36.5 36.2/35.0 33.0/33.8 40. 0/43.2 34/35 39/38
   SD 4.9/5.2 1.5/1.5 3.5/2.7 1.8/2.2 5.2/6.1 2.5/2.3 6.3/5.5
   Range 31–52/31–53 34–36/35–38 34–42/32–39 32–34/31–37 34–47/37–53 31–37/32 – 38 32–52/31–45
Left ventricular ejection fraction-%        
   Mean 73/74 71/72 71/70 74/74 75/78 71/72 74/74
   SD 5/4 2/4 5/3.5 2.5/2.1 6.7 – 6.9 1.7/2.5 7.3/4.9
   Range 62–87/66–88 68–73/66 – 75 67 – 79/66–75 71–78/71–76 67 – 83/70 – 88 68 – 73/69–74 62–87/67–81
Right ventricular enddiastolic diameter-mm        
   Mean 3.4/3.5 3.5/3.6 3.4/3.6 3.4/3.7 3.34/3.45 3.3/3.5 3.2/3.4
   SD 0.16/0.14 0.14/0.13 0.22/0.21 0.21/0.23 0.16/0.21 0.21/0.22 0.19/0.22
   Range 3.3 – 4.0/3.5 – 4.1 3.4–4.1/3.4 – 4.3 3.3–4.0/3.2 – 4.3 3.4–4.1/3.3 – 4.3 3.4–4.1/3.2–4.3 3.2–3.9/3.4 – 4.1 3.4 – 3.9/3.4 – 4.1
Tricuspid annular plane Systolic excursion (TAPSE)-mm        
   Mean 1.9/1.9 1.85/1.82 1.94/1.86 1.88/1.95 1.88/1.95 1.9/1.9 1.91/1.92
   SD 0.12/0.11 0.17/0.10 0.16/0.11 0.13/0.08 0.13/0.09 0.11/0.09 0.09/0.14
   Range 1.7 – 2.2/1.7–2.1 1.7 – 2.1/1.7 – 1.9 1.8–2.2/1.7–2.0 1.7–2.1/1.8–2.0 1.7–2.1/1.8–2.0 1.7–2.0/1.8–2.0 1.8–2.0/1.7–2.1
  1. Group 1 = control group (without operation and without medication)
  2. Group 2 = operation group without additional therapy
  3. Group 3 = combination of operation and photodynamic therapy
  4. Group 4 = operation in combination with hyperthermic intraoperative peritoneal chemotherapy with mitomycine
  5. Group 5 = operation in combination with hyperthermic intraoperative peritoneal chemotherapy with gemcitabine
  6. Group 6 = operation in combination with taurolidin i.p. instillation;
  7. * P < 0.05; ** P < 0.001