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Table 3 Main studies evaluating the accuracy of pharmacological stress echocardiography in detecting CAV and coronary artery stenosis > 50% in HT recipients (Mod from Thorn EM et al, Heart Fail Clin 2007)

From: Usefulness and limitations of transthoracic echocardiography in heart transplantation recipients

Authors

N. of pts

Time post-HT (years)

Sensitivity for CV

Specificity for CAV

Sensitivity for cor. stenosis

Sensitivity for cor. stenosis

Dobutamine

Akosah KO, 1994

41

4.8 (0.25–10)

95%

50%

100%

41%

Herregods, J Heart Lung Tr1994

28

3.2 ± 1.3

50%

71%

-

-

Derumeaux G, JACC 1995

41

3.3 ± 1.7

86%

91%

100%

77%

Derumeaux G, Arch Mal Coeur 1996

64

3.3 ± 1.2

85%

97%

100%

-

Akosah KO, JACC 1998

22

0.17 (0.04–0.3)

100%

73%

100%

59%

Derumeaux G, J Heart Lung Tr 1998

37

3.1 ± 1.7

4.7 ± 1.8

65%

92%

95%

73%

-

-

-

-

Spes GH, Circulation 1999

109

3.2 ± 3.1

72%

88%

-

-

Bacal F, J Heart Lung Tr 2004

38

> 4

-

-

64%

91%

Dipyridamole

Ciliberto GR, Eur Heart J 1993

80

2.3 ± 0.5

80%

85%

100%

72%

Ciliberto GR. J Heart Lung Tr 2003

68

2.9 ± 1.9

80%

79%

100%

87%

Adenosine

Tona F J Heart Lung Tr 2006

73

8.0 ± 4.5

82%

87%

-

-

  1. CFR = Coronary flow reserve