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Table 3 Main studies evaluating the accuracy of pharmacological stress echocardiography in detecting CAV and coronary artery stenosis > 50% in HT recipients (Mod from Thorn EM et al, Heart Fail Clin 2007)

From: Usefulness and limitations of transthoracic echocardiography in heart transplantation recipients

Authors N. of pts Time post-HT (years) Sensitivity for CV Specificity for CAV Sensitivity for cor. stenosis Sensitivity for cor. stenosis
Dobutamine
Akosah KO, 1994 41 4.8 (0.25–10) 95% 50% 100% 41%
Herregods, J Heart Lung Tr1994 28 3.2 ± 1.3 50% 71% - -
Derumeaux G, JACC 1995 41 3.3 ± 1.7 86% 91% 100% 77%
Derumeaux G, Arch Mal Coeur 1996 64 3.3 ± 1.2 85% 97% 100% -
Akosah KO, JACC 1998 22 0.17 (0.04–0.3) 100% 73% 100% 59%
Derumeaux G, J Heart Lung Tr 1998 37 3.1 ± 1.7 4.7 ± 1.8 65% 92% 95% 73% - - - -
Spes GH, Circulation 1999 109 3.2 ± 3.1 72% 88% - -
Bacal F, J Heart Lung Tr 2004 38 > 4 - - 64% 91%
Dipyridamole
Ciliberto GR, Eur Heart J 1993 80 2.3 ± 0.5 80% 85% 100% 72%
Ciliberto GR. J Heart Lung Tr 2003 68 2.9 ± 1.9 80% 79% 100% 87%
Adenosine
Tona F J Heart Lung Tr 2006 73 8.0 ± 4.5 82% 87% - -
  1. CFR = Coronary flow reserve