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Table 2 Effect of Mental Stress on Carotid Artery Vascular Responses in Young vs Older Normal Subjects

From: Cerebrovascular mental stress reactivity is impaired in hypertension

 

Young Normal (n = 10)

Older Normal (n = 20)

Variable

Baseline

Peak

Baseline

Peak

Systolic BP (mm Hg)

110 ± 7

124 ± 8*

118 ± 12

131 ± 22*

Diastolic BP (mm Hg)

69 ± 7

82 ± 6*

73 ± 10

79 ± 11*

Mean BP (mm Hg)

83 ± 6

96 ± 7*

88 ± 9

96 ± 11*

Heart Rate (bpm)

71 ± 10

87 ± 13*

69 ± 12

80 ± 17*

CA diameter (cm)

0.61 ± 0.06†

0.65 ± 0.07*

0.63 ± 0.06†

0.66 ± 0.07*

PSV (cm/s)

110 ± 23

119 ± 28

72 ± 16

76 ± 13

EDV (cm/s)

23 ± 4

25 ± 6

19 ± 6

21 ± 5*

TAM (cm)

22 ± 7

25 ± 6

18 ± 5

23 ± 6*†

RI

0.84 ± 0.1

0.79 ± 0.1*

0.73 ± 0.1

0.72 ± 0.1

PI

2.4 ± 0.7

2.1 ± 0.4

1.7 ± 0.6

1.5 ± 0.4

Flow (ml/min)

419 ± 134

541 ± 209*

351 ± 114

454 ± 136*†

  1. Values are mean ± SD. Numbers in brackets represent number of participating subjects in each group. Data represents the effects of the mental stress task that produced the maximum increase in blood flow in both groups. *p < 0.05 vs. baseline. †p < 0.05 vs. hypertensive. BP, blood pressure; PSV, peak systolic velocity; EDV, end-diastolic velocity; TAM, time average mean velocity; TAM, time averaged mean velocity. Flow = 3.14× 60× (radius)2× TAM; RI, resistive index; PI, pulsatility index.