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Table 2 Receiver operating characteristics analysis of echocardiographic parameters to predict pulmonary capillary wedge pressure ≥18 mmHg

From: Left atrial longitudinal strain by speckle tracking echocardiography correlates well with left ventricular filling pressures in patients with heart failure

  Cutoff value Sensitivity
(95% CI)(%)
Specificity
(95% CI)(%)
AUC
Two-dimensional Echo     
LV EDV >278 ml 50.0 (15.6-85.6) 88.2 (46.3-99.6) 0.60
LA area >36.5 cm2 60.0 (32.4-84.1) 50.0 (16.1-85.3) 0.68
LA volume indexed >37.8 ml/m2 67.9 (53.9-96.8) 87.5 (56.9-95.7) 0.78
Mitral flow Doppler     
Mitral E wave > 94.2 cm/s 90.1 (66.8-99.7) 66.8 (26.3-93.2) 0.72
E/A ratio >2.6 89.4 (65.1-97.2) 65.2 (24.3-92.9) 0.70
Tissue Doppler     
Mean E/Em ratio >16.8 67.9 (27.8-91.5) 93.1 (76.9-99.8) 0.69
Speckle tracking     
Global PALS <15.1% 100 (83.9-100) 93.2 (78.1-99.8) 0.93
  1. (AUC, Area under the curve; CI, confidence interval; LV, left ventricular; EDV, end diastolic volume; LA, left atrial; E, early transmitral flow velocity; A. atrial transmitral flow velocity; Em, early diastolic mitral annular velocity; PALS, peak atrial longitudinal strain).