Left atrial longitudinal strain by speckle tracking echocardiography correlates well with left ventricular filling pressures in patients with heart failure

Table 2 Receiver operating characteristics analysis of echocardiographic parameters to predict pulmonary capillary wedge pressure ≥18 mmHg

	Cutoff value	Sensitivity (95% CI)(%)	Specificity (95% CI)(%)	AUC
*Two-dimensional Echo*
LV EDV	>278 ml	50.0 (15.6-85.6)	88.2 (46.3-99.6)	0.60
LA area	>36.5 cm²	60.0 (32.4-84.1)	50.0 (16.1-85.3)	0.68
LA volume indexed	>37.8 ml/m²	67.9 (53.9-96.8)	87.5 (56.9-95.7)	0.78
*Mitral flow Doppler*
Mitral E wave	> 94.2 cm/s	90.1 (66.8-99.7)	66.8 (26.3-93.2)	0.72
E/A ratio	>2.6	89.4 (65.1-97.2)	65.2 (24.3-92.9)	0.70
*Tissue Doppler*
Mean E/Em ratio	>16.8	67.9 (27.8-91.5)	93.1 (76.9-99.8)	0.69
*Speckle tracking*
Global PALS	<15.1%	100 (83.9-100)	93.2 (78.1-99.8)	0.93

(AUC, Area under the curve; CI, confidence interval; LV, left ventricular; EDV, end diastolic volume; LA, left atrial; E, early transmitral flow velocity; A. atrial transmitral flow velocity; Em, early diastolic mitral annular velocity; PALS, peak atrial longitudinal strain).

ISSN: 1476-7120