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Table 1 Baseline characteristics of patients and their response to CRT

From: Strain dyssynchrony index determined by three-dimensional speckle area tracking can predict response to cardiac resynchronization therapy

Variable

All Patients

(14)

Responders

(9)

Non-Responders

(5)

p value

Age ( years )

70 ± 9

70 ± 8

71 ± 12

NS

Male/female

12/2

8/1

4/1

NS

NYHA functional class III/IV

12/2

8/1

4/1

NS

QRS duration (ms)

172 ± 30

178 ± 32

163 ± 26

NS

SR/AF/paced

10/0/4

6/0/3

4/0/1

NS

End-diastolic volume (ml)

175 ± 72

194 ± 82

140 ± 29

NS

End-systolic volume (ml)

132 ± 67

152 ± 76

94 ± 20

NS

Ejection fraction (%)

27 ± 7

23 ± 6

32 ± 3

NS

Heart failure etiology

    

Ischemic

5 (36%)

2 (22%)

3 (60%)

NS

Non-ischemic

9 (64%)

7 (78%)

2 (40%)

NS

Medication

    

ACEI/ARB

11 (92%)

7 (89%)

4 (100%)

NS

β-blockers

11 (92%)

7 (89%)

4 (100%)

NS

Diuretics

10 (83%)

6 (75%)

4 (100%)

NS

Area strain dyssynchrony index (%)

4.1 ± 1.4

4.8 ± 1.1

2.8 ± 0.7

< 0.005

Conventional dyssynchrony measurements (ms)

    

Yu index

49 ± 17

48 ± 19

51 ± 15

NS

IVMD

46 ± 28

53 ± 31

34 ± 15

NS

Radial dyssynchrony determined by Speckle tracking strain

233 ± 129

277 ± 114

153 ± 126

NS

  1. ACEI, angiotensin converting enzyme inhibitor; AF, atrial fibrillation; ARB, angiotensin receptor blocker; IVMD, Interventricular mechanical delay; NS, not significance; NYHA, New York Heart Association; SR, sinus rhythm.