Variable | All Patients (14) | Responders (9) | Non-Responders (5) | p value |
---|---|---|---|---|
Age ( years ) | 70 ± 9 | 70 ± 8 | 71 ± 12 | NS |
Male/female | 12/2 | 8/1 | 4/1 | NS |
NYHA functional class III/IV | 12/2 | 8/1 | 4/1 | NS |
QRS duration (ms) | 172 ± 30 | 178 ± 32 | 163 ± 26 | NS |
SR/AF/paced | 10/0/4 | 6/0/3 | 4/0/1 | NS |
End-diastolic volume (ml) | 175 ± 72 | 194 ± 82 | 140 ± 29 | NS |
End-systolic volume (ml) | 132 ± 67 | 152 ± 76 | 94 ± 20 | NS |
Ejection fraction (%) | 27 ± 7 | 23 ± 6 | 32 ± 3 | NS |
Heart failure etiology | Â | Â | Â | Â |
Ischemic | 5 (36%) | 2 (22%) | 3 (60%) | NS |
Non-ischemic | 9 (64%) | 7 (78%) | 2 (40%) | NS |
Medication | Â | Â | Â | Â |
ACEI/ARB | 11 (92%) | 7 (89%) | 4 (100%) | NS |
β-blockers | 11 (92%) | 7 (89%) | 4 (100%) | NS |
Diuretics | 10 (83%) | 6 (75%) | 4 (100%) | NS |
Area strain dyssynchrony index (%) | 4.1 ± 1.4 | 4.8 ± 1.1 | 2.8 ± 0.7 | < 0.005 |
Conventional dyssynchrony measurements (ms) | Â | Â | Â | Â |
Yu index | 49 ± 17 | 48 ± 19 | 51 ± 15 | NS |
IVMD | 46 ± 28 | 53 ± 31 | 34 ± 15 | NS |
Radial dyssynchrony determined by Speckle tracking strain | 233 ± 129 | 277 ± 114 | 153 ± 126 | NS |