Table 1 Clinical study population findings
Abnormal exercise PASP | Normal exercise PASP | P = | |
|---|---|---|---|
N of pts | 14 | 95 | |
Dilated cardiomyopathy | 1 (7%) | 8 (8.5%) | NS |
Aortic stenosis, moderate | 3 (21%) | 4 (4.2%) | < 0.05 |
Aortic regurgitation, moderate | 0 | 2 (2.1%) | NS |
Mitral stenosis, moderate | 1 (7%) | 0 | NS |
Mitral regurgitation, moderate | 4 (29%) | 3 (3.2%) | < 0.05 |
Known coronary artery disease | 3 (21%) | 45 (47.4%) | < 0.05 |
Prior myocardial infarction | 1 (7%) | 35 (37.6%) | < 0.05 |
Prior percutaneous coronary intervention | 2 (14%) | 32 (33.7%) | NS |
Arterial hypertension | 7 (50%) | 46 (48.4%) | NS |
Chronic obstructive pulmonary disease | 0 | 18 (18.9%) | < 0.05 |
Diabetes | 1 (7%) | 20 (22.7%) | NS |
Effort dyspnea | 10 (77%) | 39 (41%) | < 0.05 |
Left bundle branch block | 3 (21%) | 12 (12.6%) | NS |
Right bundle branch block | 0 | 8 (8.5%) | NS |
Therapy at the time of test | |||
β-blockers | 7 (50%) | 40 (42.1%) | NS |
Calcium antagonists | 3 (21%) | 26 (27.4%) | NS |
Nitrates | 1 (7%) | 17 (18.3%) | NS |
ACE inhibitors | 5 (36%) | 34 (36.6%) | NS |
Diuretics | 4 (29%) | 13 (13.7%) | NS |
At least one medication | 10 (71%) | 69 (72.6%) | NS |