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Table 2 Rest and stress data

From: Abnormal shortened diastolic time length at increasing heart rates in patients with abnormal exercise-induced increase in pulmonary artery pressure

 

Patients, abnormal exercise PASP

Patients, normal exercise PASP

Controls

N of patients

14

95

16

Age (years)

63 ± 12*

60 ± 12 Δ

35 ± 9

Gender (Male/Female)

8/6

70/25

14/2

Rest and stress echo measurements

   

Left ventricular mass index (g/m2)

112 ± 17

107 ± 30

99 ± 24

Heart rate rest (bpm)

65 ± 15

73 ± 15

77 ± 15

Heart rate peak (bpm)

118 ± 22*

123 ± 21 Δ

163 ± 11

Systolic blood pressure rest (mmHg)

128 ± 21

135 ± 20

126 ± 13

Systolic blood pressure peak (mmHg)

177 ± 21

186 ± 24

192 ± 27

Diastolic blood pressure rest (mmHg)

70 ± 10

75 ± 12

72 ± 10

Diastolic blood pressure peak (mmHg)

88 ± 11

94 ± 12

89 ± 13

Pulmonary artery systolic pressure rest (mmHg)

35 ± 4§

30 ± 5 Δ

25 ± 4

Pulmonary artery systolic pressure peak (mmHg)

62 ± 12§

38 ± 7 Δ

32 ± 6

LV end-diastolic volume index rest (mL/m2)

55 ± 23

52 ± 18

51 ± 13

Δ LV end-diastolic volume index (rest-peak, mL/m2)

-5 ± 15

-5 ± 9

-10 ± 11

LV end-systolic volume index rest (mL/m2)

22 ± 10

22 ± 14

21 ± 9

Δ LV end-systolic volume index (rest-peak, mL/m2)

-2 ± 6*

-4 ± 7 Δ

-10 ± 5

LV ejection fraction % rest

57 ± 14

57 ± 11

60 ± 7

Δ LV ejection fraction % (rest-peak)

1 ± 8*

5 ± 11 Δ

13 ± 9

Wall motion score index rest

1.12 ± 0.32

1.19 ± 0.37 Δ

1.00 ± 0.00

Systolic pressure/End-systolic volume index rest (mmHg/mL/m2)

8.6 ± 7.8

8.3 ± 5.4

7.1 ± 3.1

Δ Systolic pressure/End-systolic volume index (rest-peak, mmHg/mL/m2)

4.2 ± 5*

7.4 ± 7.9 Δ

14.6 ± 11.1

Arterial elastance index rest (mmHg/mL/m2)

4.3 ± 1.7

4.6 ± 1.5

4 ± 0.9

Δ Arterial elastance index (rest-peak, mmHg/mL/m2)

1.5 ± 1.8

1.7 ± 1.6

2.4 ± 2

Ventricular/arterial coupling rest (ratio)

1.7 ± 0.8

1.6 ± 0.8

1.6 ± 0.5

Δ Ventricular/arterial coupling (rest-peak)

0.4 ± 1.1

0.7 ± 1.3

1.6 ± 1.8

Cardiac index rest (L/min/m2)

1.99 ± 0.74

2.01 ± 0.70

2.19 ± 0.51

Δ Cardiac index (rest-peak, L/min/m2)

1.36 ± 0.94*

1.44 ± 0.95 Δ

2.58 ± 1.77

Sensor built Force-Frequency Relation

   

Force rest (g * 10-3)

12.6 ± 10

9.7 ± 5.3 Δ

16.6 ± 7.4

Δ Force (rest-peak, g * 10-3)

21.4 ± 21.7*

22.5 ± 21.4 Δ

53.1 ± 33

Sensor recorded diastolic and systolic times

   

Diastolic time at 80 bpm (msec)

415 ± 30 §

438 ± 25 Δ

470 ± 29

Diastolic time at 100 bpm (msec)

304 ± 19 §

323 ± 21 Δ

350 ± 22

Diastolic time at 110 bpm (msec)

264 ± 16 §

286 ± 21 Δ

306 ± 21

Systolic time at 80 bpm (msec)

335 ± 30 §

312 ± 25 Δ

280 ± 29

Systolic time at 100 bpm (msec)

303 ± 19 §

276 ± 21 Δ

250 ± 22

Systolic time at 110 bpm (msec)

281 ± 16 §

259 ± 21 Δ

239 ± 21

Diastolic/systolic time ratio at 80 bpm

1.26 ± 0.20 §

1.42 ± 0.20 Δ

1.76 ± 0.34

Diastolic/systolic time ratio at 100 bpm

1.01 ± 0.12 §

1.18 ± 0.17 Δ

1.42 ± 0.22

Diastolic/systolic time ratio at 110 bpm

0.95 ± 0.11 §

1.12 ± 0.17 Δ

1.29 ± 0.20

Diastolic/systolic time ratio at recovery, 100 bpm

1.24 ± 0.28 *

1.48 ± 0.28 Δ

1.75 ± 0.41

  1. § = significant differences between abnormal stress PASP patients vs. both normal stress PASP patients and Controls; ‡ = significant differences between abnormal stress PASP patients vs. normal stress PASP patients; * = significant differences between abnormal stress PASP patients vs. Controls. Δ = significant differences between normal stress PASP patients vs. Controls.
  2. g = 9.8 m/sec2; PASP, pulmonary artery systolic pressure
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Cardiovascular Ultrasound

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