Table 1 Baseline characteristics of the total study population and in subgroups of non-severe vs. severe AS
From: Myocardial function in aortic stenosis – insights from radial multilayer Doppler strain
All (n = 84) | Non-severe AS (n = 38) | Severe AS (n = 46) | |
|---|---|---|---|
Age (years) | 73 ± 10 | 70 ± 10 | 76 ± 8* |
Women | 56% | 50% | 61% |
Body mass index (kg/m2) | 25.2 ± 4.0 | 25.4 ± 3.8 | 25.0 ± 4.2 |
Heart rate (beats /minute) | 65 ± 10 | 64 ± 9 | 66 ± 10 |
Hypertension | 56% | 61% | 52% |
Systolic blood pressure (mm Hg) | 149 ± 20 | 148 ± 17 | 149 ± 23 |
Diastolic blood pressure (mm Hg) | 79 ± 12 | 81 ± 11 | 77 ± 12 |
Ejection fraction (%) | 63 ± 7 | 64 ± 6 | 62 ± 8 |
Circumferential end-systolic stress (dyne/cm2) | 135 ± 44 | 134 ± 43 | 135 ± 45 |
Peak systolic stress (dyne/cm2) | 242 ± 74 | 253 ± 83 | 234 ± 66 |
LV mass (g) | 217 ± 73 | 206 ± 74 | 226 ± 71 |
LV hypertrophy | 57% | 45% | 67%‡ |
Concentric LV geometry | 60% | 42% | 74%† |
Aortic valve area index (cm2/m2) | 0.53 ± 0.20 | 0.69 ± 0.17 | 0.40 ± 0.09* |
ELI (cm2/m2) | 0.60 ± 0.25 | 0.81 ± 0.22 | 0.44 ± 0.10* |
EndoS (%) | 53.0 ± 40.0 | 70.5 ± 37.6 | 38.4 ± 36.2* |
MidS (%) | 50.3 ± 37.3 | 60.1 ± 43.1 | 42.1 ± 29.7‡ |
EpiS (%) | 33.4 ± 38.6 | 41.5 ± 47.4 | 26.7 ± 28.1 |