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Table 1 Baseline characteristics of the total study population and in subgroups of non-severe vs. severe AS

From: Myocardial function in aortic stenosis – insights from radial multilayer Doppler strain

  All (n = 84) Non-severe AS (n = 38) Severe AS (n = 46)
Age (years) 73 ± 10 70 ± 10 76 ± 8*
Women 56% 50% 61%
Body mass index (kg/m2) 25.2 ± 4.0 25.4 ± 3.8 25.0 ± 4.2
Heart rate (beats /minute) 65 ± 10 64 ± 9 66 ± 10
Hypertension 56% 61% 52%
Systolic blood pressure (mm Hg) 149 ± 20 148 ± 17 149 ± 23
Diastolic blood pressure (mm Hg) 79 ± 12 81 ± 11 77 ± 12
Ejection fraction (%) 63 ± 7 64 ± 6 62 ± 8
Circumferential end-systolic stress (dyne/cm2) 135 ± 44 134 ± 43 135 ± 45
Peak systolic stress (dyne/cm2) 242 ± 74 253 ± 83 234 ± 66
LV mass (g) 217 ± 73 206 ± 74 226 ± 71
LV hypertrophy 57% 45% 67%‡
Concentric LV geometry 60% 42% 74%†
Aortic valve area index (cm2/m2) 0.53 ± 0.20 0.69 ± 0.17 0.40 ± 0.09*
ELI (cm2/m2) 0.60 ± 0.25 0.81 ± 0.22 0.44 ± 0.10*
EndoS (%) 53.0 ± 40.0 70.5 ± 37.6 38.4 ± 36.2*
MidS (%) 50.3 ± 37.3 60.1 ± 43.1 42.1 ± 29.7‡
EpiS (%) 33.4 ± 38.6 41.5 ± 47.4 26.7 ± 28.1
  1. Data are mean ± SD or percentage. * p <0.001, † p <0.01, and ‡ p <0.05. LV = left ventricular; ELI = energy loss index; EndoS, MidS and EpiS = peak systolic radial strain in the subendocardial, midmyocardial, and subepicardial layers of the left ventricular inferior wall.