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Table 4 Estimated fetal weight and biological parameters: Comparison between the affected fetuses with different degrees of tricuspid regurgitation and gestational age-matched controls

From: Evaluation of right ventricular function in fetal hypoplastic left heart syndrome using spatio-temporal image correlation (STIC)

Group N Gestational age (weeks) RVCO/EFW (mL/min/kg) RVCO/HC (mL/min/cm) RVCO/AC (mL/min/cm) RVCO/FL (mL/min/cm)
Control 151 30.16 ± 3.85 207.01 ± 31.59 11.30 ± 4.02 11.92 ± 3.86 54.84 ± 18.43
HLHS-mild TR 29 29.43 ± 3.64 280.00 ± 63.62* 13.70 ± 3.32* 14.62 ± 3.58* 63.24 ± 13.90*
HLHS-severe TR 10 28.61 ± 2.60 224.32 ± 61.64# (P = 0.013) 10.85 ± 3.16# (P = 0.006) 11.66 ± 3.23# (P = 0.015) 53.59 ± 15.66# (P = 0.008)
  1. Abbreviations: HLHS hypoplastic left heart syndrome, TR tricuspid regurgitation, RVCO right ventricular cardiac output, EFW estimated fetal weight, HC head circumference, AC abdominal circumference, FL femur length
  2. * P < 0.001 vs. control group, after adjusting for gestational age; # P < 0.05 vs. HLHS-mild TR, after adjusting for gestational age