Table 2 HR for primary and secondary end points by univariate Cox proportional hazard regression analysis

MACCEs

HR (95 % CI)

p

HR (95 % CI)

p

HR (95 % CI)

p

HR (95 % CI)

p

All Patients

2.1 (1.4–3.1)

0.000#

1.2 (0.7–2.2)

0.457

2.2 (1.3–2.7)

0.003*

3.1 (2.0–4.9)

0.000#

CABG Patients

2.1 (1.3–3.2)

0.001*

1.8 (0.7–4.5)

0.201

3.2 (1.2–7.9)

0.013*

6.1 (2.6–14.1)

0.000#

Valve Patients

2.7 (1.2–6.0)

0.011*

1.6 (0.5–4.9)

0.402

2.9 (1.1–7.7)

0.025*

3.3 (1.4–8.0)

0.005#

 Aortic stenosis

6.6 (0.8–51)

0.071

0.1 (0.1–1.0)

0.521

1.9 (0.3–11)

0.482

1.6 (0.2–9.6)

0.060

 Aortic regurgitation

4.2 (1.5–11)

0.004*

3.3 (0.7–15)

0.117

3.7 (1.1–12)

0.028*

4.5 (1.5–13)

0.006*

 Mitral regurgitaton

4.2 (1.5–11)

0.004*

1.9 (0.1–31)

0.638

6.4 (0.7–57)

0.096

7.0 (0.9–57)

0.067

Valve + CABG

2.3 (0.9–5.6)

0.053

1.6 (0.4–6.3)

0.484

2.4 (0.7–7.8)

0.122

2.6 (0.9–7.1)

0.050

All-cause mortality

1.6 (0.9–2.8)

0.064

1.2 (0.5–2.7)

0.533

1.6 (0.7–3.5)

0.258

2.2 (1.1–4.2)

0.025*

CV mortality

2.2 (1.0–4.5)

0.032*

1.2 (0.4–3.7)

0.739

2.5 (0.9–6.6)

0.070

3.1 (1.3–7.4)

0.010*

Heart failure

1.8 (0.9–3.5)

0.057

0.8 (0.2–2.5)

0.796

2.5 (1.0–5.8)

0.034*

2.5 (1.1–5.4)

0.023*

Stroke

1.6 (0.5–4.8)

0.327

1.0 (0.2–5.3)

0.918

n.a.

n.a.

3.8 (1.2–11.9)

0.019*

n.a.

ACS

1.9 (0.8–4.4)

0.137

1.5 (0.4–4.9)

0.492

1.6 (0.4–5.9)

0.483

2.6 (0.9–7.4)

0.067