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Table 3 Determinants of limited exercise in HF patients

From: Different determinants of exercise capacity in HFpEF compared to HFrEF

Variable OR (CI 95%) P value
Determinants of all HF study patients
 Univariate determinants
  Age 1.062 (1.014–1.112) 0.011
  Diabetes mellitus 0.353 (0.150–0.892) 0.017
  NYHA class >1 0.290 (0.108–0.783) 0.015
  LVMI 1.035 (1.011–1.060) 0.004
  Left atrium 2.410 (1.404–4.137) 0.001
  E wave 1.023 (1.004–1.043) 0.019
  FT 0.996 (0.993–1.000) 0.036
  Heart rate 1.039 (1.010–1.069) 0.008
  PAAC 0.972 (0.952–0.993) 0.010
  E/e’ 1.092 (1.009–1.181) 0.028
  Septal a’ 0.786 (0.631–0.979) 0.032
  Septal s’ 0.661 (0.444–0.984) 0.041
 Multivariate determinants
  Left atrium diameter 2.676 (1.242–5.766) 0.012
  Diabetes mellitus 0.274 (0.084–0.898) 0.033
  Age 1.067 (0.999–1.140) 0.052
  NYHA class >1 2.068 (0.859–4.978) 0.105
  Gender 0.406 (0.122–1.350) 0.141
  E/e’ 1.043 (0.943–1.153) 0.415
  FT 0.997 (0.989–1.005) 0.463
  Septal s’ 0.854 (0.512–1.422) 0.543
  Heart rate 1.011 (0.940–1.088) 0.764
Determinants in HFpEF patients
 Univariate determinants
  Diabetes mellitus 0.276 (0.082–0.926) 0.037
  Haemoglobin 0.697 (0.502–0.968) 0.031
  NYHA class >1 0.206 (0.043–0.993) 0.049
  BSA 0.005 (0.000–0.308) 0.012
  LVMI 1.049 (1.006–1.094) 0.025
  Lateral a’ 0.772 (0.603–0.987) 0.039
  Lateral s’ 0.489 (0.270–0.886) 0.018
 Multivariate determinants
  Lateral s’ 0.295 (0.099–0.882) 0.029
  Haemoglobin 0.497 (0.248–0.998) 0.049
  NYHA class >1 0.051 (0.003–1.034) 0.053
  BSA 0.081 (0.000–6.016) 0.463
  Lateral a’ 1.049 (0.734–1.500) 0.793
  Age 0.988 (0.827–1.179) 0.891
  Diabetes 0.860 (0.109–6.786) 0.886
Determinants in HFrEF patients
 Univariate determinants
  Age 1.067 (1.010–1.127) 0.020
  Left atrium 3.236 (1.333–7.856) 0.009
  LAV max 1.021 (1.001–1.042) 0.045
  LAV min 1.029 (1.003–1.055) 0.032
 Multivariate determinants
  Age 1.073 (1.012–1.137) 0.018
  Left atrium diameter 3.685 (1.348–10.071) 0.011
  Gender 2.147 (0.556–8.288) 0.268
  1. BMI body mass index, BSA body surface area, NYHA New York Heart Association, LV left ventricle, EDD end-diastolic dimension, ESD end-systolic dimension, FT filling time, ET ejection time, PA pulmonary artery, A atrial diastolic velocity, E early diastolic filling velocity, e’ early diastolic myocardial velocity, s’ systolic myocardial velocity, LVMI left ventricular mass index