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Table 5 Multivariable-adjusted associations between ejection work density and echocardiographic indexes of left ventricular diastolic function

From: Area of the pressure-strain loop during ejection as non-invasive index of left ventricular performance: a population study

 

Ejection work density (Pa)

 
 

All (n = 356)

Men (n = 197)

Women (n = 159)

 

LV diastolic function index

Parameter estimate (95% CI)

P value

Parameter estimate (95% CI)

P value

Parameter estimate (95% CI)

P value

P int

E peak, + 15 cm/s

55.3 (33.0 to 77.5)

< 0.0001

38.8 (11.3 to 66.3)

0.0059

86.7 (51.2 to 122.3)

< 0.0001

0.39

A peak, + 15 cm/s

47.2 (20.6 to 73.8)

0.0005

43.9 (9.50 to 78.2)

0.013

45.5 (39.0 to 87.2)

0.032

0.16

E/A ratio, + 0.45

29.1 (−2.30 to 60.4)

0.069

17.0 (−20.9 to 54.9)

0.38

58.3 (5.50 to 111.1)

0.031

0.39

e’ peak, + 3.2 cm/s

32.2 (−0.031 to 64.3)

0.050

48.6 (10.3 to 87.0)

0.013

16.5 (−36.7 to 72.7)

0.56

0.014

a’ peak, + 2.0 cm/s

19.7 (−4.97 to 44.4)

0.12

33.9 (5.42 to 52.3)

0.020

−8.96 (−51.9 to 34.0)

0.68

0.75

E/e’ ratio, + 2.1

32.1 (9.20 to 55.1)

0.0062

2.45 (−31.1 to 36.1)

0.89

51.1 (19.6 to 82.6)

0.0017

0.0016

  1. The parameter estimates (95% confidence interval) indicate the change in EWD per 1 standard deviation increase in the LV diastolic function index. All parameter estimates accounted for the variance explained by age, sex, heart rate and body height and weight. Pint represents the P value for an interaction between each LV diastolic function index and sex in predicting EWD