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Table 5 Multivariable-adjusted associations between ejection work density and echocardiographic indexes of left ventricular diastolic function

From: Area of the pressure-strain loop during ejection as non-invasive index of left ventricular performance: a population study

  Ejection work density (Pa)  
  All (n = 356) Men (n = 197) Women (n = 159)  
LV diastolic function index Parameter estimate (95% CI) P value Parameter estimate (95% CI) P value Parameter estimate (95% CI) P value P int
E peak, + 15 cm/s 55.3 (33.0 to 77.5) < 0.0001 38.8 (11.3 to 66.3) 0.0059 86.7 (51.2 to 122.3) < 0.0001 0.39
A peak, + 15 cm/s 47.2 (20.6 to 73.8) 0.0005 43.9 (9.50 to 78.2) 0.013 45.5 (39.0 to 87.2) 0.032 0.16
E/A ratio, + 0.45 29.1 (−2.30 to 60.4) 0.069 17.0 (−20.9 to 54.9) 0.38 58.3 (5.50 to 111.1) 0.031 0.39
e’ peak, + 3.2 cm/s 32.2 (−0.031 to 64.3) 0.050 48.6 (10.3 to 87.0) 0.013 16.5 (−36.7 to 72.7) 0.56 0.014
a’ peak, + 2.0 cm/s 19.7 (−4.97 to 44.4) 0.12 33.9 (5.42 to 52.3) 0.020 −8.96 (−51.9 to 34.0) 0.68 0.75
E/e’ ratio, + 2.1 32.1 (9.20 to 55.1) 0.0062 2.45 (−31.1 to 36.1) 0.89 51.1 (19.6 to 82.6) 0.0017 0.0016
  1. The parameter estimates (95% confidence interval) indicate the change in EWD per 1 standard deviation increase in the LV diastolic function index. All parameter estimates accounted for the variance explained by age, sex, heart rate and body height and weight. Pint represents the P value for an interaction between each LV diastolic function index and sex in predicting EWD