Skip to main content

Table 2 The meta-analysis of myocardial strain and LVEF between DMD and control groups

From: Usefulness of speckle-tracking echocardiography for early detection in children with Duchenne muscular dystrophy: a meta-analysis and trial sequential analysis

Parameter

Test of difference

Test of Heterogeneity

Statistical Model

Test of Publication Bias Egger’s P-value

Sensitivity Analysis

WMD (95% CI)

P value

I2 (%)

P value

Odds Ratio (95% CI) min

Odds Ratio (95% CI) max

GLS

4.17 (3.03–5.32)

< 0.001

62.0

0.010

Random

0.498

3.81 (2.76–4.86)

4.56 (3.75–5.36)

GCS

3.98 (0.29–7.68)

0.034

92.2

< 0.001

Random

0.023

1.93 (−0.23–3.88)

5.61 (0.32–10.90)

GRS

−4.33 (−9.53–0.87)

0.103

72.2

0.027

Random

0.525

−6.35 (−12.82–0.12)

−1.61 (−4.72–1.51)

LS

4.18 (2.75–5.62)

< 0.001

35.0

0.215

Fixed

–

3.60 (1.89–5.31)

5.60 (2.94–8.26)

CS

4.90 (2.38–7.43)

< 0.001

85.6

< 0.001

Random

0.085

3.74 (1.65–5.82)

6.05 (3.17–8.92)

LVEF

−1.00 (−2.70–0.70)

0.249

76.5

< 0.001

Random

0.651

−1.45 (−3.19–0.28)

−0.37 (− 1.94–1.19)

  1. CI confidence interval, CS circumferential strain, DMD Duchenne muscular dystrophy, GCS global circumferential strain, GLS global longitudinal strain, GRS global radial strain, LS longitudinal strain, LVEF left ventricular ejection fraction, WMD weighted mean difference. Significant results are marked in bold