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Table 2 The meta-analysis of myocardial strain and LVEF between DMD and control groups

From: Usefulness of speckle-tracking echocardiography for early detection in children with Duchenne muscular dystrophy: a meta-analysis and trial sequential analysis

Parameter Test of difference Test of Heterogeneity Statistical Model Test of Publication Bias Egger’s P-value Sensitivity Analysis
WMD (95% CI) P value I2 (%) P value Odds Ratio (95% CI) min Odds Ratio (95% CI) max
GLS 4.17 (3.03–5.32) < 0.001 62.0 0.010 Random 0.498 3.81 (2.76–4.86) 4.56 (3.75–5.36)
GCS 3.98 (0.29–7.68) 0.034 92.2 < 0.001 Random 0.023 1.93 (−0.23–3.88) 5.61 (0.32–10.90)
GRS −4.33 (−9.53–0.87) 0.103 72.2 0.027 Random 0.525 −6.35 (−12.82–0.12) −1.61 (−4.72–1.51)
LS 4.18 (2.75–5.62) < 0.001 35.0 0.215 Fixed 3.60 (1.89–5.31) 5.60 (2.94–8.26)
CS 4.90 (2.38–7.43) < 0.001 85.6 < 0.001 Random 0.085 3.74 (1.65–5.82) 6.05 (3.17–8.92)
LVEF −1.00 (−2.70–0.70) 0.249 76.5 < 0.001 Random 0.651 −1.45 (−3.19–0.28) −0.37 (− 1.94–1.19)
  1. CI confidence interval, CS circumferential strain, DMD Duchenne muscular dystrophy, GCS global circumferential strain, GLS global longitudinal strain, GRS global radial strain, LS longitudinal strain, LVEF left ventricular ejection fraction, WMD weighted mean difference. Significant results are marked in bold