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Table 3 Univariable and multivariable binary logistic regression analysis for association with stroke in patients with normal (iLAVmax< 34 ml/m2) and abnormal (iLAVmax ≥34 ml/m2) LA volumes

From: Comparison of left atrial and left atrial appendage mechanics in the risk stratification of stroke in patients with atrial fibrillation

Norma LA volumes

Univariable

Multivariable

N = 81, stroke = 10

OR (95% CI)

P

Model 1

Model 2

Model 3

Model 4

Model 5

Model 6

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

CHA2DS2-VASc score

1.26 (0.73–2.18)

0.40

            

LA GLS (%)

0.88 (0.79–0.97)

0.01

  

0.97 (0.86–1.08)

0.56

0.88 (0.79–0.97)

0.01

0.86 (0.77–0.97)

< 0.01

0.87 (0.77–0.97)

< 0.01

0.88 (0.79–0.99)

0.04

LA MD (%)

1.51 (1.16–1.97)

< 0.01

1.51 (1.16–1.97)

< 0.01

  

1.51 (1.16–1.97)

< 0.01

1.85 (1.23–2.79)

< 0.01

1.55 (1.15–2.09)

< 0.01

1.66 (1.13–2.42)

< 0.01

LAEF(%)

0.94 (0.89–0.98)

0.01

0.97 (0.91–1.03)

0.28

0.97 (0.92–1.04)

0.40

  

0.94 (0.89–0.99)

0.02

0.95 (0.90–1.01)

0.11

0.95 (0.90–1.01)

0.09

LAAEV (cm/s)

1.96 (0.01–4.36)

0.70

0.87 (0.33–22.89)

0.21

1.00 (0.05–19.73)

0.89

1.97 (0.07–55.22)

0.24

  

1.00 (0.05–20.46)

0.98

0.47 (0.02–9.61)

0.63

LAA GLS(%)

0.80 (0.65–0.99)

0.05

0.90 (0.72–1.13)

0.36

0.92 (0.75–1.12)

0.39

0.80 (0.65–1.00)

0.05

0.80 (0.65–0.99)

0.05

  

0.85 (0.68–1.06)

0.15

LAA MD (%)

1.31 (1.06–1.61)

0.01

1.26 (0.99–1.61)

0.06

1.33 (0.99–1.77)

0.06

1.28 (1.02–1.60)

0.03

1.31 (1.06–1.61)

0.01

1.27 (1.01–1.59)

0.04

  

Abnormal LA volumes

Univariable

Multivariable

N = 127, stroke = 21

OR (95% CI)

P

Model 1

Model 2

Model 3

Model 4

Model 5

Model 6

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

CHA2DS2-VASc score

1.47 (1.00–2.14)

0.05

            

LA GLS (%)

0.93 (0.84–1.02)

0.10

  

0.99 (0.92–1.08)

0.33

0.93 (0.84–1.02)

0.10

0.89 (0.81–1.00)

0.05

0.93 (0.83–1.05)

0.26

0.90 (0.81–1.01)

0.07

LA MD (%)

1.18 (1.02–1.35)

0.03

1.18 (1.02–1.35)

0.03

  

1.18 (1.02–1.35)

0.01

1.21 (1.04–1.41)

0.01

1.17 (0.99–1.36)

0.05

1.16 (0.99–1.35)

0.06

LAEF (%)

0.99 (0.96–1.02)

0.41

1.01 (0.97–1.05)

0.90

0.98 (0.95–1.01)

0.54

  

0.99 (0.95–1.03)

0.56

0.99 (0.95–1.03)

0.65

0.99 (0.95–1.02)

0.42

LAAEV (cm/s)

0.02 (0.00–0.76)

0.04

0.15 (0.01–4.29)

0.34

0.10 (0.01–2.71)

0.16

0.03 (0.01–0.94)

0.05

  

0.06 (0.01–2.52)

0.14

0.05 (0.01–2.22)

0.12

LAA GLS (%)

0.85 (0.73–0.98)

0.02

0.84 (0.72–0.98)

0.02

0.91 (0.79–1.06)

0.06

0.84 (0.72–0.97)

0.02

0.85 (0.73–0.98)

0.02

  

0.91 (0.78–1.06)

0.22

LAA MD (%)

1.17 (1.05–1.31)

< 0.01

1.16 (1.04–1.30)

< 0.01

1.15 (1.03–1.29)

0.01

1.17 (1.05–1.30)

< 0.01

1.16 (1.04–1.30)

< 0.01

1.17 (1.05–1.31)

< 0.01

  
  1. Model 1 adjusted with CHA2DS2-VASc score and LA GLS
  2. Model 2 adjusted with CHA2DS2-VASc score and LA MD
  3. Model 3 adjusted with CHA2DS2-VASc score and LAEF
  4. Model 4 adjusted with CHA2DS2-VASc score and LAAEV
  5. Model 5 adjusted with CHA2DS2-VASc score and LAA GLS
  6. Model 6 adjusted with CHA2DS2-VASc score and LAA MD
  7. AF atrial fibrillation, CI Confidence intervals, GLS global longitudinal strain, i indexed to body surface area, LA left atrium, LAA left atrial appendage, LAAEV LAA emptying velocity, LAEF LA emptying fraction, MD mechanical dispersion, OR odds ratio, Vmax maximal volume