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Table 3 Univariable and multivariable binary logistic regression analysis for association with stroke in patients with normal (iLAVmax< 34 ml/m2) and abnormal (iLAVmax ≥34 ml/m2) LA volumes

From: Comparison of left atrial and left atrial appendage mechanics in the risk stratification of stroke in patients with atrial fibrillation

Norma LA volumes Univariable Multivariable
N = 81, stroke = 10 OR (95% CI) P Model 1 Model 2 Model 3 Model 4 Model 5 Model 6
OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P
CHA2DS2-VASc score 1.26 (0.73–2.18) 0.40             
LA GLS (%) 0.88 (0.79–0.97) 0.01    0.97 (0.86–1.08) 0.56 0.88 (0.79–0.97) 0.01 0.86 (0.77–0.97) < 0.01 0.87 (0.77–0.97) < 0.01 0.88 (0.79–0.99) 0.04
LA MD (%) 1.51 (1.16–1.97) < 0.01 1.51 (1.16–1.97) < 0.01    1.51 (1.16–1.97) < 0.01 1.85 (1.23–2.79) < 0.01 1.55 (1.15–2.09) < 0.01 1.66 (1.13–2.42) < 0.01
LAEF(%) 0.94 (0.89–0.98) 0.01 0.97 (0.91–1.03) 0.28 0.97 (0.92–1.04) 0.40    0.94 (0.89–0.99) 0.02 0.95 (0.90–1.01) 0.11 0.95 (0.90–1.01) 0.09
LAAEV (cm/s) 1.96 (0.01–4.36) 0.70 0.87 (0.33–22.89) 0.21 1.00 (0.05–19.73) 0.89 1.97 (0.07–55.22) 0.24    1.00 (0.05–20.46) 0.98 0.47 (0.02–9.61) 0.63
LAA GLS(%) 0.80 (0.65–0.99) 0.05 0.90 (0.72–1.13) 0.36 0.92 (0.75–1.12) 0.39 0.80 (0.65–1.00) 0.05 0.80 (0.65–0.99) 0.05    0.85 (0.68–1.06) 0.15
LAA MD (%) 1.31 (1.06–1.61) 0.01 1.26 (0.99–1.61) 0.06 1.33 (0.99–1.77) 0.06 1.28 (1.02–1.60) 0.03 1.31 (1.06–1.61) 0.01 1.27 (1.01–1.59) 0.04   
Abnormal LA volumes Univariable Multivariable
N = 127, stroke = 21 OR (95% CI) P Model 1 Model 2 Model 3 Model 4 Model 5 Model 6
OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P
CHA2DS2-VASc score 1.47 (1.00–2.14) 0.05             
LA GLS (%) 0.93 (0.84–1.02) 0.10    0.99 (0.92–1.08) 0.33 0.93 (0.84–1.02) 0.10 0.89 (0.81–1.00) 0.05 0.93 (0.83–1.05) 0.26 0.90 (0.81–1.01) 0.07
LA MD (%) 1.18 (1.02–1.35) 0.03 1.18 (1.02–1.35) 0.03    1.18 (1.02–1.35) 0.01 1.21 (1.04–1.41) 0.01 1.17 (0.99–1.36) 0.05 1.16 (0.99–1.35) 0.06
LAEF (%) 0.99 (0.96–1.02) 0.41 1.01 (0.97–1.05) 0.90 0.98 (0.95–1.01) 0.54    0.99 (0.95–1.03) 0.56 0.99 (0.95–1.03) 0.65 0.99 (0.95–1.02) 0.42
LAAEV (cm/s) 0.02 (0.00–0.76) 0.04 0.15 (0.01–4.29) 0.34 0.10 (0.01–2.71) 0.16 0.03 (0.01–0.94) 0.05    0.06 (0.01–2.52) 0.14 0.05 (0.01–2.22) 0.12
LAA GLS (%) 0.85 (0.73–0.98) 0.02 0.84 (0.72–0.98) 0.02 0.91 (0.79–1.06) 0.06 0.84 (0.72–0.97) 0.02 0.85 (0.73–0.98) 0.02    0.91 (0.78–1.06) 0.22
LAA MD (%) 1.17 (1.05–1.31) < 0.01 1.16 (1.04–1.30) < 0.01 1.15 (1.03–1.29) 0.01 1.17 (1.05–1.30) < 0.01 1.16 (1.04–1.30) < 0.01 1.17 (1.05–1.31) < 0.01   
  1. Model 1 adjusted with CHA2DS2-VASc score and LA GLS
  2. Model 2 adjusted with CHA2DS2-VASc score and LA MD
  3. Model 3 adjusted with CHA2DS2-VASc score and LAEF
  4. Model 4 adjusted with CHA2DS2-VASc score and LAAEV
  5. Model 5 adjusted with CHA2DS2-VASc score and LAA GLS
  6. Model 6 adjusted with CHA2DS2-VASc score and LAA MD
  7. AF atrial fibrillation, CI Confidence intervals, GLS global longitudinal strain, i indexed to body surface area, LA left atrium, LAA left atrial appendage, LAAEV LAA emptying velocity, LAEF LA emptying fraction, MD mechanical dispersion, OR odds ratio, Vmax maximal volume