Baseline | Post-3d | Post-1 m | Post-6 m | P1 | P2 | P3 | |
---|---|---|---|---|---|---|---|
E (cm/s) | 66.3 ± 18.6 | 67.7 ± 16.9 | 66.0 ± 20.8 | 66.5 ± 15.8 | 0.582 | 0.561 | 0.850 |
A (cm/s) | 81.4 ± 22.7 | 86.9 ± 26.7 | 87.5 ± 23.2 | 85.5 ± 20.4 | 0.072 | 0.882 | 0.585 |
E/A | 0.9 ± 0.4 | 0.8 ± 0.4 | 0.8 ± 0.3 | 0.9 ± 0.3 | 0.959 | 0.491 | 0.896 |
DT (ms) | 216.2 ± 50.6 | 188.1 ± 39.3 | 193.0 ± 34.0 | 196.4 ± 26.4 | 0.003* | 0.540 | 0.514 |
IVRT(ms) | 107.1 ± 12.1 | 91.0 ± 12.3 | 84.6 ± 9.1 | 82.8 ± 9.3 | < 0.001* | 0.007* | 0.273 |
E’ (cm/s) | 6.5 ± 2.1 | 6.9 ± 1.8 | 8.0 ± 2.3 | 8.6 ± 1.6 | 0.356 | 0.018* | 0.047* |
E/E’ | 10.8 ± 3.7 | 10.3 ± 3.3 | 7.9 ± 3.0 | 7.2 ± 2.1 | 0.403 | 0.012* | 0.063 |
LA area (cm2) | 22.9 ± 4.6 | 21.4 ± 3.8 | 18.6 ± 3.0 | 17.2 ± 2.3 | < 0.001* | < 0.001* | < 0.001* |
LAVI (ml/cm2) | 42.4 ± 14.7 | 38.7 ± 11.3 | 31.3 ± 8.3 | 27.5 ± 5.5 | 0.008* | < 0.001* | < 0.001* |
TR (m/s) | 3.3 ± 0.5 | 2.9 ± 0.5 | 2.7 ± 0.4 | 2.6 ± 0.3 | < 0.001* | 0.021* | 0.143 |