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Table 1 Baseline characteristics of the study patients (n = 47)

From: 2D-echocardiography vs cardiac MRI strain: a prospective cohort study in patients with HER2-positive breast cancer undergoing trastuzumab

Age, years 57.0 (50.0, 63.0)
55.0 (10.1)
BMI, kg/m2 24.5 (23.1, 29.4)
25.9 (4.8)
Breast cancer
 Early-stage 38 (81)
 Advanced-stage 9 (19)
 Anthracycline-based chemotherapy 38 (81)
 Left-sided radiotherapy 12 (26)
Cardiovascular risk factors
 Hypertension 17 (36)
 Diabetes mellitus 3 (6)
 Hypercholesterolemia 7 (15)
 Positive family history 15 (32)
 Current or ever smoker 13 (28)
Cardiac condition before treatment
 Valve insuffiency 0 (0)
 Arrhytmia 1 (2)
 MI/CABG/PCI 0 (0)
Cardiovascular medication
 Beta-blockers 1 (2)
 ACE inhibitors 2 (4)
 Both 1 (2)
CMR imaging parameters
 LVEF, % 60.4 (55.8, 66.0)
60.6 (7.3)
 GLS, % -18.7 (−20.1, −16.9)
−18.1 (5.6)
 GRS, % 30.1 (24.5, 32.9)
29.5 (5.8)
 Left ventricular mass, g 73.6 (65.4, 88.0)
76.3 (15.2)
 Length left ventricle diastolic phase, mm 86.0 (81.5, 89.5)
85.9 (6.6)
 LGE, % 6.0 (5.0–8.0)
6.9 (3.1)
2DE parameters
 LVEF, % 66.0 (63.0, 73.0)
67.5 (6.5)
 ST-LVEF, % 57.2 (53.3, 62.6)
56.9 (8.1)
 ST-GLS, % −18.8 (− 20.6, −16.3)
−18.4 (3.0)
 ST-GRS, % 21.4 (13.5, 34.1)
23.6 (13.1)
  1. All continuous variables are shown as median + IQR, mean + SD
  2. Abbreviations: BMI body mass index, MI myocardial infarction, CABG coronary arterial bypass grafting, PCI percutaneous coronary intervention, ACE angiotensin converting enzyme, CMR cardiac magnetic resonance imaging, 2DE two-dimensional echocardiography, LVEF left ventricular ejection fraction, GLS global longitudinal strain, GRS global radial strain, LGE late gadolinium enhancement