Skip to main content

Table 2 Galectin-3 and sST2 levels in various subgroups of the study population

From: Galectin-3 and sST2: associations to the echocardiographic markers of the myocardial mechanics in systemic sclerosis – a pilot study

Clinical variable Galectin-3 sST2
Level (ng/ml) p* Level (ng/ml) p*
Female patients (n = 36; 90%) 13.2 ± 4.1 0.123 27.3 ± 9.8 0.207
Male patients (n = 4; 10%) 9.6 ± 0.2 40.1 ± 18.7
Limited cutaneous form (n = 12; 30%) 12.9 ± 3.1 0.805 30.1 ± 9.5 0.389
Diffuse cutaneous form (n = 28; 70%) 12.9 ± 4.4 27.9 ± 12.1
Anti-centromere antibody positive (n = 8; 20%) 11.3 ± 2.8 0.354 28.6 ± 9.4 0.871
Anti-centromere antibody negative (n = 32; 80%) 13.0 ± 4.1 29.1 ± 11.8
Anti-topoisomerase antibody positive (n = 19; 47.5%) 12.8 ± 4.5 0.901 27.0 ± 8.6 0.989
Anti-topoisomerase antibody negative (n = 21; 52.5%) 12.8 ± 3.7 29.5 ± 13.6
Patients with diabetes (n = 2; 5%) 13.4 ± 6.3 0.877 36.5 ± 15.2 0.400
Patients without diabetes (n = 38; 95%) 12.8 ± 4.0 28.1 ± 11.2
Current smokers (n = 3; 7.5%) 11.5 ± 5.5 0.518 30.7 ± 27.4 0.518
Non-smokers (n = 37; 92.5%) 13.1 ± 3.8 26.9 ± 9.4
Hypertension (n = 25; 62.5%) 13.3 ± 3.9 0.581 26.9 ± 9.6 0.391
No hypertension (n = 15; 37.5%) 12.2 ± 4.3 31.2 ± 13.6
Treated with angiotensin convertase enzyme inhibitors (n = 12; 30%) 14.1 ± 3.6 0.218 26.6 ± 9.0 0.938
Not treated with angiotensin convertase enzyme inhibitors (n = 28; 70%) 12.3 ± 4.1 28.4 ± 12.0
Treated with calcium channel blockers (n = 18; 45%) 12.8 ± 3.6 0.925 27.1 ± 10.3 0.545
Not treated with calcium channel blockers (n = 22; 55%) 12.9 ± 4.4 29.7 ± 12.2
Treated with loop diuretics (n = 12; 30%) 15.5 ± 3.8 0.006 25.5 ± 7.9 0.457
Not treated with loop diuretics (n = 28; 70%) 11.7 ± 3.6 29.8 ± 12.4
Treated with mineralocorticoid receptor antagonists (n = 10; 25%) 13.5 ± 4.3 0.569 29.7 ± 10.5 0.432
Not treated with mineralocorticoid receptor antagonists (n = 30; 75%) 12.7 ± 4.0 28.1 ± 11.7
Treated with pentoxifylline (n = 20; 50%) 12.8 ± 3.6 0.758 28.4 ± 11.3 0.968
Not treated with pentoxifylline (n = 20;50%) 12.9 ± 4.5 28.7 ± 11.6
  1. * Mann–Whitney U-test. Statistically significant p-values (p < 0.05) are formatted in bold