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Table 4 Correlations of galectin-3 (ln) and ST2 (ln) with the echocardiographic parameters of the RV and RA size and mechanics in SSc patients

From: Galectin-3 and sST2: associations to the echocardiographic markers of the myocardial mechanics in systemic sclerosis – a pilot study

Parameter

Value

Correlations with ln galectin-3

Correlations with ln galectin-3,

corrected for age

Correlations with ln ST2

Correlations with ln ST2,

corrected for age

r

p

r

p

r

p

r

p

Pulmonary artery systolic pressure (mm Hg)

28.6 ± 7.5

0.225

0.251

0.260

0.191

−0.174

0.375

−0.188

0.348

RV basal diameter index (mm/m2)

18.3 ± 2.4

−0.254

0.119

−0.253

0.126

−0.015

0.928

−0.015

0.928

RV mid-cavity diameter index (mm/m2)

13.0 ± 2.1

−0.169

0.311

−0.169

0.318

−0.037

0.827

−0.037

0.828

RV longitudinal diameter index (mm/m2)

30.0 ± 3.6

−0.011

0.948

−0.011

0.948

−0.342

0.135

−0.341

0.148

Inferior vena cava (mm)

13.2 ± 3.9

−0.053

0.765

−0.052

0.775

−0.255

0.146

−0.254

0.153

Collapsibility index (%)

55.2 ± 10.7

0.134

0.449

0.134

0.457

−0.131

0.462

−0.132

0.465

RV wall thickness (mm)

5.1 ± 1.2

−0.091

0.597

−0.106

0.545

−0.051

0.766

−0.086

0.622

RV fractional area change (%)

47.9 ± 6.8

−0.138

0.423

−0.142

0.415

−0.001

0.997

0.013

0.943

Tricuspid annular plane systolic excursion (mm)

21.4 ± 2.6

−0.249

0.121

−0.243

0.136

0.315

0.248

0.321

0.284

Grade of tricuspid regurgitation

Mild n (%)

38 (95%)

0.168

0.307

0.165

0.321

−0.105

0.523

− 0.105

0.530

Moderate n (%)

2 (5%)

Severe n (%)

0 (0%)

Tricuspid E cm/s

47.4 ± 8.0

−0.073

0.658

−0.087

0.602

−0.060

0.751

−0.050

0.767

Tricuspid A cm/s

40.1 ± 8.5

0.371

0.020

0.372

0.022

−0.160

0.330

−0.162

0.331

Tricuspid S (cm/s)

12.4 ± 2.0

−0.170

0.293

−0.169

0.305

0.363

0.221

0.363

0.227

Tricuspid e’ (cm/s)

10.0 ± 2.8

−0.038

0.817

−0.009

0.956

0.006

0.972

0.001

0.996

Tricuspid a’ (cm/s)

13.1 ± 2.9

−0.100

0.539

−0.147

0.372

0.154

0.342

0.182

0.267

Tricuspid E/e’ ratio

5.2 ± 1.6

0.003

0.985

0.004

0.983

−0.001

0.995

−0.008

0.963

RA Vmax index (mL/m2)

19.9 ± 5.8

−0.013

0.947

0.017

0.929

−0.048

0.800

−0.101

0.602

RA Vmin index (mL/m2)

8.1 ± 4.0

0.227

0.227

0.245

0.201

−0.136

0.473

−0.163

0.397

RA Vp index (mL/m2)

14.3 ± 5.5

0.058

0.760

0.083

0.668

−0.112

0.555

−0.156

0.419

RA reservoir strain (%)

45.3 ± 9.0

−0.239

0.167

−0.236

0.179

0.218

0.209

0.229

0.193

RA conduit strain (%)

24.2 ± 6.4

−0.213

0.220

−0.210

0.233

0.199

0.253

0.220

0.212

RA contractile strain (%)

22.0 ± 6.1

−0.220

0.204

−0.231

0.188

0.065

0.713

0.056

0.753

  1. Statistically significant p-values are formatted in bold (p < 0.05)
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Cardiovascular Ultrasound

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