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Table 4 Correlations of galectin-3 (ln) and ST2 (ln) with the echocardiographic parameters of the RV and RA size and mechanics in SSc patients

From: Galectin-3 and sST2: associations to the echocardiographic markers of the myocardial mechanics in systemic sclerosis – a pilot study

Parameter Value Correlations with ln galectin-3 Correlations with ln galectin-3,
corrected for age
Correlations with ln ST2 Correlations with ln ST2,
corrected for age
r p r p r p r p
Pulmonary artery systolic pressure (mm Hg) 28.6 ± 7.5 0.225 0.251 0.260 0.191 −0.174 0.375 −0.188 0.348
RV basal diameter index (mm/m2) 18.3 ± 2.4 −0.254 0.119 −0.253 0.126 −0.015 0.928 −0.015 0.928
RV mid-cavity diameter index (mm/m2) 13.0 ± 2.1 −0.169 0.311 −0.169 0.318 −0.037 0.827 −0.037 0.828
RV longitudinal diameter index (mm/m2) 30.0 ± 3.6 −0.011 0.948 −0.011 0.948 −0.342 0.135 −0.341 0.148
Inferior vena cava (mm) 13.2 ± 3.9 −0.053 0.765 −0.052 0.775 −0.255 0.146 −0.254 0.153
Collapsibility index (%) 55.2 ± 10.7 0.134 0.449 0.134 0.457 −0.131 0.462 −0.132 0.465
RV wall thickness (mm) 5.1 ± 1.2 −0.091 0.597 −0.106 0.545 −0.051 0.766 −0.086 0.622
RV fractional area change (%) 47.9 ± 6.8 −0.138 0.423 −0.142 0.415 −0.001 0.997 0.013 0.943
Tricuspid annular plane systolic excursion (mm) 21.4 ± 2.6 −0.249 0.121 −0.243 0.136 0.315 0.248 0.321 0.284
Grade of tricuspid regurgitation Mild n (%) 38 (95%) 0.168 0.307 0.165 0.321 −0.105 0.523 − 0.105 0.530
Moderate n (%) 2 (5%)
Severe n (%) 0 (0%)
Tricuspid E cm/s 47.4 ± 8.0 −0.073 0.658 −0.087 0.602 −0.060 0.751 −0.050 0.767
Tricuspid A cm/s 40.1 ± 8.5 0.371 0.020 0.372 0.022 −0.160 0.330 −0.162 0.331
Tricuspid S (cm/s) 12.4 ± 2.0 −0.170 0.293 −0.169 0.305 0.363 0.221 0.363 0.227
Tricuspid e’ (cm/s) 10.0 ± 2.8 −0.038 0.817 −0.009 0.956 0.006 0.972 0.001 0.996
Tricuspid a’ (cm/s) 13.1 ± 2.9 −0.100 0.539 −0.147 0.372 0.154 0.342 0.182 0.267
Tricuspid E/e’ ratio 5.2 ± 1.6 0.003 0.985 0.004 0.983 −0.001 0.995 −0.008 0.963
RA Vmax index (mL/m2) 19.9 ± 5.8 −0.013 0.947 0.017 0.929 −0.048 0.800 −0.101 0.602
RA Vmin index (mL/m2) 8.1 ± 4.0 0.227 0.227 0.245 0.201 −0.136 0.473 −0.163 0.397
RA Vp index (mL/m2) 14.3 ± 5.5 0.058 0.760 0.083 0.668 −0.112 0.555 −0.156 0.419
RA reservoir strain (%) 45.3 ± 9.0 −0.239 0.167 −0.236 0.179 0.218 0.209 0.229 0.193
RA conduit strain (%) 24.2 ± 6.4 −0.213 0.220 −0.210 0.233 0.199 0.253 0.220 0.212
RA contractile strain (%) 22.0 ± 6.1 −0.220 0.204 −0.231 0.188 0.065 0.713 0.056 0.753
  1. Statistically significant p-values are formatted in bold (p < 0.05)