Table 2 Univariable Cox regression model
From: Biochemical but not imaging parameters are predictive of outcome in septic shock: a pilot study
Variables | S group (n = 20) | NS group (n = 15) | P | HR | 95%CI |
|---|---|---|---|---|---|
Age, years | 56 (46; 68) | 64 (54; 73) | 0.203 | 1.027 | 0.986–1.071 |
Gender F, n (%) | 9 (45%) | 5 (33%) | 0.563 | 0.728 | 0.249–2.131 |
GSH RB, μmol/L | 410 (318; 561) | 392 (202; 518) | 0.370 | 0.998 | 0.995–1.002 |
GSH TP, μmol/L | 4.24 (2.118; 6.228) | 2.73 (2.18; 4.18) | 0.200 | 0.833 | 0.630–1.102 |
Hcy TP, μmol/L | 8.03 (5.92; 14.13) | 9.40 (5.48; 15.40) | 0.681 | 1.013 | 0.952–1.078 |
CysGly TP, μmol/L | 35 (25; 47) | 29 (20; 36) | 0.454 | 0.987 | 0.953–1.022 |
Cys TP, μmol/L | 147 (100; 206) | 168 (108; 232) | 0.708 | 1.001 | 0.998–1.003 |
MDA, mmol/L | 147 (97; 184) | 206 (120; 261) | 0.074 | 1.004 | 1.000–1.008 |
3-NT nmol/L | 12.33 (7.12; 22.65) | 12.33 (6.70; 38.10) | 0.688 | 0.999 | 0.994–1.004 |
uNEO, μmol/mmol Creat | 1.068 (0.528; 1.908) | 1.344 (0.822; 3.436) | 0.099 | 1.212 | 0.964–1.524 |
IL-6 pg/mL | 446 (49; 2540) | 1198 (180; 8646) | 0.146 | 1.000 | 1.000–1.000 |
sIL-6R pg/mL | 31,136 (20,251; 51,166) | 33,157 (10,896; 38,651) | 0.185 | 1.000 | 1.000–1.000 |
sGP-130 ng/mL | 236 (202; 286) | 200 (170; 307) | 0.685 | 0.999 | 0.991–1.006 |
Ang-1 pg/mL, (500-fold increment) | 10,200 (4614; 31,953) | 11,062 (4480; 28,900) | 0.848 | 0.999 | 0.985–1.013 |
Ang-2 pg/mL, (500-fold increment) | 26,950 (10,822; 43,840) | 49,048 (33,483; 64,293) | 0.003 | 1.007 | 1.002–1.012 |
TnT, ng/L | 105 (36; 289) | 91 (50; 160) | 0.495 | 1.000 | 1.000–1.000 |
NTproBNP, ng/L | 19,359 (1991; 31,044) | 7558 (3150; 28,820) | 0.679 | 1.000 | 1.000–1.000 |
PCT, ng/mL | 34 (11; 100) | 35 (9; 70) | 0.696 | 0.997 | 0.983–1.011 |
PWV, cm/sec | 10.3 (8.7; 11.8) | 10.8 (8.4; 11.7) | 0.931 | 1.009 | 0.829–1.228 |
AX, % | 8 (−7; 33) | 12 (4; 15) | 0.840 | 1.003 | 0.974–1.033 |
VTD, ml | 108 (82; 116) | 93 (60; 108) | 0.220 | 0.985 | 0.961–1.009 |
VTS, ml | 39 (32; 49) | 39 (29; 61) | 0.962 | 1.001 | 0.967–1.035 |
Dtd, mm | 49 (41; 54) | 45 (40; 49) | 0.185 | 0.926 | 0.826–1.038 |
EF, % | 55 (40; 64) | 55 (39; 61) | 0.702 | 0.992 | 0.952–1.034 |
MAPSE, mm | 12.5 (12.0; 15.5) | 12.5 (11.5; 14.3) | 0.779 | 0.965 | 0.752–1.239 |
E, cm/sec | 91 (56; 116) | 85 (65; 90) | 0.466 | 0.989 | 0.962–1.018 |
A, cm/sec | 73 (40; 110) | 90 (64; 111) | 0.472 | 1.009 | 0.985–1.032 |
E/e’ | 8.55 (5.75; 12.93) | 7.40 (5.95; 13.10) | 0.998 | 1.000 | 0.833–1.201 |
Left atrial area, cm2 | 21 (17; 26) | 19 (17; 23) | 0.277 | 0.920 | 0.792–1.069 |
TAPSE, mm | 20 (16; 23) | 19 (15; 23) | 0.958 | 0.997 | 0.877–1.132 |
PAPs, mmHg | 36 (35; 46) | 34 (30; 41) | 0.277 | 0.941 | 0.844–1.050 |