This article has Open Peer Review reports available.
Acute hemodynamic effect of inhaled iloprost in pulmonary artery hypertension evaluated with echocardiography
© Loureiro et al; licensee BioMed Central Ltd. 2007
Received: 25 October 2007
Accepted: 21 November 2007
Published: 21 November 2007
Doppler echocardiography is useful in the initial evaluation and long-term follow-up of patients with pulmonary artery hypertension. Aerosolised iloprost has been shown to reduce pulmonary pressure immediately after inhalation. We report the echocardiographic findings in a patient with severe pulmonary hypertension, before and after the inhalation of aerosolized iloprost. These findings illustrate the acute influence of iloprost in right and left ventricular hemodynamics and morphology. These findings were reproduced in subsequent echocardiographic evaluations.
Additional file 3: Three-dimensional parasternal view before iloprost inhalation. Three-dimensional parasternal long axis view before iloprost inhalation showing a small left ventricle with increased eccentricity index. (AVI 9 MB)
Additional file 4: Three-dimensional parasternal view after iloprost inhalation. Three-dimensional parasternal long axis view after iloprost inhalation showing near normal morphology of both ventricles. (AVI 8 MB)
The findings that we describe showed the potential utility of echocardiography in the evaluation of the acute effects of drugs used in the treatment of pulmonary arterial hypertension.
Written informed consent was obtained for publication from the patient.
- Bossone E, Bodini B, Mazza A, Allegra L: Pulmonary arterial hypertension. The key role of echocardiography. Chest. 2005, 127: 1836-1843. 10.1378/chest.127.5.1836.View ArticlePubMedGoogle Scholar
- Burgess M, Bright-Thomas R, Ray S: Echocardiographic evaluation of right ventricular function. Eur J Echocardiography. 2002, 3: 252-262.Google Scholar
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.