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Echocardiographic manifestation of hiatus hernia simulating a left atrial mass: Case report
© Koskinas et al; licensee BioMed Central Ltd. 2008
Received: 03 August 2008
Accepted: 15 September 2008
Published: 15 September 2008
Despite the high prevalence of hiatus hernia, a relatively small number of echocardiographically manifested cases have been reported.
An 82-year old woman presented with acute retrosternal pain indicative of cardiac etiology. Physical examination and biochemical tests, as well as 12-lead electrocardiogram, were normal. A two-dimensional transthoracic echocardiogram was performed and revealed a structure that was considered to represent a left atrial mass. A subsequent computed tomography scan visualized a hiatus hernia in the posterior mediastinum, impinging on the posterior left atrial wall. The intrathoracic displacement of a large part of the stomach was further confirmed by an upper gastrointestinal barium examination.
Hiatus hernia can present as acute chest pain, while its echocardiographic manifestation may resemble a left atrial space-occupying structure. Physicians should be aware of the clinical and sonographic findings to facilitate the differential diagnosis from similarly presenting cardiac entities.
Hiatus hernia is a frequent entity, characterized by the displacement of the gastroesophageal junction and part of the stomach into the mediastinum. Although it may produce symptoms suggestive of cardiac etiology, only few cases of its echocardiographic manifestation have been reported. We present the case of a patient with an apparent left atrial mass on transthoracic echocardiography, which was subsequently identified as hiatus hernia.
An 82-year-old woman presented to the Emergency Department complaining of sudden onset chest pain radiating to the epigastrium at rest, with less than 1 hour of duration. Her medical history included chronic heart failure and she was therefore treated with digitalis 0,25 mg/day. On initial examination her blood pressure was 130/80 mmHg. A grade 3/6 holosystolic murmur was audible at the apex. Her lungs were clear to percussion and auscultation. The 12-lead electrocardiogram (ECG) demonstrated sinus rhythm with non-specific "scooping" ST-segment depression in leads III, aVF, V4–V6, attributable to her current medication. Laboratory tests, including cardiac enzymes and cardiac troponin-I, were within normal reference values. The patient was admitted to the Cardiology Department for further investigation.
Additional file 1: Movie of transthoracic echocardiography. This movie shows a parasternal long-axis echocardiographic view during one cardic cycle demonstrating an apparent left atrial mass. (AVI 10 MB)
After excluding the cardiac origin of the clinical presentation, based on serial ECG and biochemical findings, conservative treatment was opted and the patient was discharged two days after admission.
Written consent was obtained from the patient for publication of study.
Although often asymptomatic, hiatus hernia may present with caustic epigastralgia and regurgitation due to concommitant gastroesophageal reflux. It may also exert a wide spectrum of manifestations mimicking acute cardiovascular events. It has thus been implicated with postprandial syncope  and angina-like chest pain . ECG changes may result in the misdiagnosis of myocardial ischemia . The clinical presentation of hiatus hernia-induced cardiac compression can range from dyspnea to impaired respiratory function , recurrent acute heart failure  and ultimately hemodynamic collapse . Further cardiac complications include the formation of gastropericardial fistula , pericardial effusion  and arrhythmia . Hiatus hernia can hinder the sonographic depiction of the cardiac anatomy  and has been reported to simulate the appearance of an intra-atrial mass [9–12] or a posterior mediastinal structure on transthoracic echocardiography [1, 3, 5].
The intravenous infusion of echocardiographic contrast medium may facilitate the characterization of the investigated structure, according to the degree of enhancement (parallel to the vascular density) and the communication with cardiac chambers . The visualization of swirling echodensities following the oral ingestion of carbonated beverage , particularly in combination with echocardiographic contrast media , furhter enhances the differential diagnosis. These techniques were regrettably not employed in the present case, inevitably at the expense of the cost-effectiveness of the diagnostic approach, radiation exposure and patient inconvenience.
Various intracardiac or extrinsic lesions can resemble the echocardiographic appearance of hiatus hernia. These include vascular formations, such as descending aorta aneurysm or dilation of the coronary sinus, and inflammatory conditions, as in the case of a mitral ring abscess. Myxoma represents the most frequent primary cardiac tumor. Secondary tumors can infiltrate the cardiac wall per continuitatem, or constitute hematogenous metastases. The augmentation of the mass depiction on posterior imaging planes, the disparate degree of encroachment on the left atrium attributable to respiratory motion  and the identification of an inner lining reminiscent of gastric mucosa  may distinguish hiatus hernia from similarly presenting structures.
Hiatus hernia can simulate clinical and sonographic characteristics of cardiac disorders. Its echocardiographic manifestation may mimic a left atrial space-occupying structure; it therefore merits attention for the differentiation from such lesions. Although the definite diagnosis is usually confirmed by other imaging modalities, adequate data can be derived from the appropriate acquisition and interpretation of echocardiographic findings.
Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.
- Oishi Y, Ishimoto T, Nagase N, Mori K, Fujimoto S, Hayashi S, Ochi Y, Kobayashi K, Tabata T, Oki T: Syncope upon swallowing caused by an esophageal hiatal hernia compressing the left atrium: a case report. Echocardiography. 2004, 21: 61-64. 10.1111/j.0742-2822.2004.03005.x.View ArticlePubMedGoogle Scholar
- Akdemir I, Davutoglu V, Aktaran S: Giant hiatal hernia presenting with stable angina pectoris and syncope. Angiology. 2001, 52: 863-865. 10.1177/000331970105201209.View ArticlePubMedGoogle Scholar
- Hokamaki J, Kawano H, Miyamoti S, Sugiyama S, Fukushima R, Sakamoto T, Yoshimura M, Ogawa H: Dynamic Electrocardiographic Changes due to Cardiac Compression by a Giant Hiatal Hernia. Intern Med. 2005, 44: 136-140. 10.2169/internalmedicine.44.136.View ArticlePubMedGoogle Scholar
- Ueda T, Mizushige K: Large hiatus hernia compressing the heart and impairing the respiratory function. J Cardiol. 2003, 41: 211-212.PubMedGoogle Scholar
- Siu CW, Jim MH, Ho HH, Cho F, Chan HW, Lau CP, Tse HF: Recurrent acute heart failure caused by sliding hiatus hernia. Postgrad Med J. 2005, 81: 268-269. 10.1136/pgmj.2004.023416.View ArticlePubMedPubMed CentralGoogle Scholar
- Raza ST, Mukherjee SK, Danias PG, Abraham J, Johnsos KM, Sands MJ, Werner MS, Silverman DI: Hemodynamically significant extrinsic left atrial compression by gastric structures in the mediastinum. Ann Intern Med. 1995, 123: 114-116.View ArticlePubMedGoogle Scholar
- Monro JL, Nicholls RJ, Hately W, Murray RS, Flavell G: Gastropericardial fistula – a complication of hiatus hernia. Br J Surg. 1974, 61: 445-447. 10.1002/bjs.1800610607.View ArticlePubMedGoogle Scholar
- Bowles MH, Lipman RE: Hiatal hernia: the "X" factor in transesophageal echocardiography. J Am Soc Echocardiogr. 1993, 6: 631-633.View ArticlePubMedGoogle Scholar
- Nishimura RA, Tajik AJ, Schattenberg TT, Seward JB: Diaphragmatic hernia mimicking an atrial mass: A two-dimensional echocardiographic pitfall. J Am Coll Cardiol. 1985, 5: 992-995.View ArticlePubMedGoogle Scholar
- Yang SS, Wagner P, Dennis C: Images in cardiovascular medicine. Hiatal Hernia Masquerading as Left Atrial Mass. Circulation. 1996, 93: 836-View ArticlePubMedGoogle Scholar
- Baerman JM, Hogan L, Swiryn S: Diaphragmatic hernia producing symptoms and signs of a left atrial mass. Am Heart J. 1988, 116: 198-200. 10.1016/0002-8703(88)90272-4.View ArticlePubMedGoogle Scholar
- Ker J, Van Beljon J: Diaphragmatic hernia mimicking an atrial mass: a two-dimensional echocardiographic pitfall and a cause of postprandial syncope. Cardiovasc J S Afr. 2004, 15 (4): 182-183.PubMedGoogle Scholar
- Smelley M, Lang RM: Large Mass Impinging on the Left Atrium: Diagnostic Value of a New Cocktail. J Am Soc Echocardiogr. 2007, 20 (12): 1414.e5-1414.e7. 10.1016/j.echo.2007.05.010.View ArticleGoogle Scholar
- D'Cruz IA, Hancock HL: Echocardiographic characteristics of diaphragmatic hiatus hernia. Am J Cardiol. 1995, 75: 308-310. 10.1016/0002-9149(95)80049-X.View ArticlePubMedGoogle Scholar
- Frans EE, Nanda NC, Patel V, Vengala S, Mehmood F, Fonbah WS, Bodiwala K: Transesophageal Two-Dimensional Echocardiographic Identification of Hiatal Hernia. Echocardiography. 2005, 22 (6): 533-535. 10.1111/j.1540-8175.2005.50017.x.View ArticlePubMedGoogle Scholar
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