Though left ventricular pseudoaneurysm formation after myocardial infarction has become a less common event in the era of reperfusion therapy, its diagnosis and management still represents a challenge in the light of its potentially catastrophic consequences. The typical clinical scenario is that of persistent or recurrent symptoms, usually of heart failure, chest pain and dyspnea, after an acute ischemic event [6, 7]. In this case, the fact that the myocardial infarction occurred unnoticed made the diagnosis more challenging and precluded the establishment of a time interval between myocardial infarction and the appearance of the pseudoaneurysm.
Echocardiography is a reasonable first diagnostic tool in these cases and, despite the unusual location at the apex, the characteristic imaging features of myocardial wall discontinuity and the presence of a neck smaller than the aneurismal cavity, together with the echogenic pericardial effusion, made it easy to attain a confident diagnosis of pseudoaneurysm, confirmed both during surgery and by the pathologic examination .
Most patients with left ventricular pseudoaneurysms after myocardial infarction have severe multivessel disease on preoperative coronary angiography. In a review by Eren and colleagues, of 14 patients who underwent surgery for left ventricular pseudoaneurysm after myocardial infarction, 10 had 3-vessel disease and 4 had 2-vessel disease . In another report from the Cleveland Clinic, Atik and colleagues, in a series of 30 patients who underwent left ventricular pseudoaneurysm repair after myocardial infarction, found only 2 patients without significant coronary lesions .
When myocardial infarction occurs in patients with normal coronary arteries it is usually considered secondary to coronary spasm or coronary thrombosis. We found a case report of left ventricular pseudoaneurysm caused by coronary spasm that resulted in a silent myocardial infarction .
Myocardial bridging of the coronary arteries, generally considered a benign congenital anomaly, has been reported in association with serious, sometimes fatal cardiovascular events like sudden cardiac death and myocardial infarction [9–11]. Prevalence varies substantially according to the modality and criteria used for detection, being much higher with intravascular ultrasound or at autopsy than with angiography . Myocardial bridges are most commonly located in the left anterior descending artery and although the tunnelled segment is typically spared, the segment proximal to the bridge frequently shows atherosclerotic plaque formation .
In recent years, new diagnostic tools such as quantitative coronary angiography, intravascular ultrasound, and intracoronary Doppler flow velocity measurements available in the catheterization laboratory, have greatly contributed to the understanding of the pathophysiologic mechanisms and etiologic factors of ischemic events associated with myocardial bridging. Although the criteria that justify the link between cardiac events and myocardial bridging have not yet been clearly identified, in this patient several factors placed him at an increased risk for cardiac events associated with myocardial bridging, namely the length and severity of diameter reduction of the coronary artery and the presence of delayed persistence of diastolic diameter reduction .